BRD-K94012289_OSI-027_LNCAP_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K94012289_OSI-027_LNCAP_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ARID5B AT rich interactive domain 5B (MRF1-like)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL9A3 collagen, type IX, alpha 3
CRYAB crystallin, alpha B
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
GABARAPL1 GABA(A) receptor-associated protein like 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AC histone cluster 1, H2ac
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
JADE2 jade family PHD finger 2
KLF6 Kruppel-like factor 6
LAMA3 laminin, alpha 3
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MCOLN1 mucolipin 1
NPC1 Niemann-Pick disease, type C1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLCB4 phospholipase C, beta 4
PTGIS prostaglandin I2 (prostacyclin) synthase
RABGAP1L RAB GTPase activating protein 1-like
RIOK3 RIO kinase 3
RSAD2 radical S-adenosyl methionine domain containing 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SMAD3 SMAD family member 3
SPP1 secreted phosphoprotein 1
SYNM synemin, intermediate filament protein
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
AGR2 anterior gradient 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CSTA cystatin A (stefin A)
CXCL9 chemokine (C-X-C motif) ligand 9
DDIT4 DNA-damage-inducible transcript 4
HSPA1A heat shock 70kDa protein 1A
IL1R2 interleukin 1 receptor, type II
JMJD6 jumonji domain containing 6
KRT81 keratin 81, type II
MAT2A methionine adenosyltransferase II, alpha
NVL nuclear VCP-like
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RGCC regulator of cell cycle
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TMSB15A thymosin beta 15a
TPPP3 tubulin polymerization-promoting protein family member 3