BRD-K94012289_OSI-027_HS578T_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-K94012289_OSI-027_HS578T_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
C5AR1 complement component 5a receptor 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
CXCL10 chemokine (C-X-C motif) ligand 10
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FZD7 frizzled class receptor 7
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXC6 homeobox C6
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
KRT17 keratin 17, type I
LAMA3 laminin, alpha 3
LAMB1 laminin, beta 1
LEF1 lymphoid enhancer-binding factor 1
LIMA1 LIM domain and actin binding 1
MFAP5 microfibrillar associated protein 5
NELL2 NEL-like 2 (chicken)
NPY1R neuropeptide Y receptor Y1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAN2 PAN2 poly(A) specific ribonuclease subunit
RBP4 retinol binding protein 4, plasma
RPL39L ribosomal protein L39-like
S100A2 S100 calcium binding protein A2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
THBS1 thrombospondin 1
TM4SF1 transmembrane 4 L six family member 1
VCAN versican

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
CHL1 cell adhesion molecule L1-like
DDIT4 DNA-damage-inducible transcript 4
DMD dystrophin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HSPA1A heat shock 70kDa protein 1A
IL6R interleukin 6 receptor
ITM2C integral membrane protein 2C
PLAC8 placenta-specific 8
RRAGD Ras-related GTP binding D
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100P S100 calcium binding protein P
SATB1 SATB homeobox 1
TM9SF3 transmembrane 9 superfamily member 3
TXN thioredoxin