BRD-K94012289_OSI-027_HA1E_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

113 genes differentially expressed following the BRD-K94012289_OSI-027_HA1E_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
AREG amphiregulin
ARG1 arginase 1
ARID5B AT rich interactive domain 5B (MRF1-like)
CD24 CD24 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COCH cochlin
CPM carboxypeptidase M
CTSG cathepsin G
DCN decorin
DEFA4 defensin, alpha 4, corticostatin
DEFB1 defensin, beta 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
ELANE elastase, neutrophil expressed
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HMGB3 high mobility group box 3
HSPA2 heat shock 70kDa protein 2
IDE insulin-degrading enzyme
INHBA inhibin, beta A
INSM1 insulinoma-associated 1
IRS2 insulin receptor substrate 2
KLK10 kallikrein-related peptidase 10
KRT14 keratin 14, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP9 matrix metallopeptidase 9
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
OLFM4 olfactomedin 4
PLAU plasminogen activator, urokinase
PLBD1 phospholipase B domain containing 1
PPARG peroxisome proliferator-activated receptor gamma
PRSS8 protease, serine, 8
RAB25 RAB25, member RAS oncogene family
RFTN1 raftlin, lipid raft linker 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SESN1 sestrin 1
SFN stratifin
SFRP4 secreted frizzled-related protein 4
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRY2 sprouty homolog 2 (Drosophila)
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TERT telomerase reverse transcriptase
TPP1 tripeptidyl peptidase I
TRAPPC6A trafficking protein particle complex 6A
TUBB2B tubulin, beta 2B class IIb
TYRP1 tyrosinase-related protein 1
VCAN versican
XIST X inactive specific transcript (non-protein coding)
ZNF586 zinc finger protein 586
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD6 abhydrolase domain containing 6
ACAT2 acetyl-CoA acetyltransferase 2
ACKR3 atypical chemokine receptor 3
ADGRG1 adhesion G protein-coupled receptor G1
AK4 adenylate kinase 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
ALDOC aldolase C, fructose-bisphosphate
APOA1 apolipoprotein A-I
ARG2 arginase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CTSZ cathepsin Z
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DUSP3 dual specificity phosphatase 3
EGLN3 egl-9 family hypoxia-inducible factor 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FAM162A family with sequence similarity 162, member A
FKBP11 FK506 binding protein 11, 19 kDa
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GATA2 GATA binding protein 2
GLIPR1 GLI pathogenesis-related 1
GPER1 G protein-coupled estrogen receptor 1
HAT1 histone acetyltransferase 1
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
IQGAP2 IQ motif containing GTPase activating protein 2
KLF4 Kruppel-like factor 4 (gut)
LMO4 LIM domain only 4
MARS methionyl-tRNA synthetase
MEIS1 Meis homeobox 1
METTL7A methyltransferase like 7A
NKX3-1 NK3 homeobox 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OAT ornithine aminotransferase
ODC1 ornithine decarboxylase 1
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PHGDH phosphoglycerate dehydrogenase
PID1 phosphotyrosine interaction domain containing 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PON2 paraoxonase 2
PRKCB protein kinase C, beta
RBP1 retinol binding protein 1, cellular
RBPMS RNA binding protein with multiple splicing
RHOC ras homolog family member C
SCARB1 scavenger receptor class B, member 1
SELENBP1 selenium binding protein 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SPAG4 sperm associated antigen 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC2 stanniocalcin 2
TARS threonyl-tRNA synthetase
TGFBI transforming growth factor, beta-induced, 68kDa
WT1 Wilms tumor 1