BRD-K94012289_OSI-027_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K94012289_OSI-027_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA1 annexin A1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLDN3 claudin 3
CLEC11A C-type lectin domain family 11, member A
CRABP2 cellular retinoic acid binding protein 2
DSP desmoplakin
EGR1 early growth response 1
GRB7 growth factor receptor-bound protein 7
KIAA0355 KIAA0355
KLK6 kallikrein-related peptidase 6
LXN latexin
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NID2 nidogen 2 (osteonidogen)
PFKL phosphofructokinase, liver
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SPRED2 sprouty-related, EVH1 domain containing 2
VCAN versican
VTCN1 V-set domain containing T cell activation inhibitor 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
AGR2 anterior gradient 2
CXCL13 chemokine (C-X-C motif) ligand 13
DCN decorin
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
JCHAIN joining chain of multimeric IgA and IgM
MUC5B mucin 5B, oligomeric mucus/gel-forming
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NKG7 natural killer cell granule protein 7
NUPR1 nuclear protein, transcriptional regulator, 1
PDGFA platelet-derived growth factor alpha polypeptide
PNP purine nucleoside phosphorylase
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
SFTPA2 surfactant protein A2
SRSF3 serine/arginine-rich splicing factor 3