BRD-K94012289_OSI-027_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K94012289_OSI-027_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AFF1 AF4/FMR2 family, member 1
C10ORF10 chromosome 10 open reading frame 10
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLPTM1 cleft lip and palate associated transmembrane protein 1
COL4A2 collagen, type IV, alpha 2
CXCL12 chemokine (C-X-C motif) ligand 12
EGR1 early growth response 1
FZD7 frizzled class receptor 7
GLUL glutamate-ammonia ligase
GPX3 glutathione peroxidase 3
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HBP1 HMG-box transcription factor 1
IRS2 insulin receptor substrate 2
LAMP1 lysosomal-associated membrane protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NMU neuromedin U
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RNMT RNA (guanine-7-) methyltransferase
SS18 synovial sarcoma translocation, chromosome 18
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TSPYL5 TSPY-like 5
TXNIP thioredoxin interacting protein
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMIGO2 adhesion molecule with Ig-like domain 2
AUTS2 autism susceptibility candidate 2
CREB1 cAMP responsive element binding protein 1
DCN decorin
DKK3 dickkopf WNT signaling pathway inhibitor 3
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SFTPB surfactant protein B
SOBP sine oculis binding protein homolog (Drosophila)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1