BRD-K94012289_OSI-027_BT20_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K94012289_OSI-027_BT20_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BASP1 brain abundant, membrane attached signal protein 1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
FBN2 fibrillin 2
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GRB7 growth factor receptor-bound protein 7
HBP1 HMG-box transcription factor 1
HMGB2 high mobility group box 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ISLR immunoglobulin superfamily containing leucine-rich repeat
KDM3A lysine (K)-specific demethylase 3A
LDLRAD4 low density lipoprotein receptor class A domain containing 4
RNF103 ring finger protein 103
SCYL3 SCY1-like 3 (S. cerevisiae)
SFRP1 secreted frizzled-related protein 1
THBS4 thrombospondin 4

decreased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
CXCL14 chemokine (C-X-C motif) ligand 14
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
FOLR1 folate receptor 1 (adult)
GPX3 glutathione peroxidase 3
HAS2 hyaluronan synthase 2
HSPB8 heat shock 22kDa protein 8
IFI27 interferon, alpha-inducible protein 27
KRT13 keratin 13, type I
LGALS1 lectin, galactoside-binding, soluble, 1
NRIP1 nuclear receptor interacting protein 1
OLFML3 olfactomedin-like 3
PAM peptidylglycine alpha-amidating monooxygenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLIN2 perilipin 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa