BRD-K94012289_OSI-027_BT20_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

100 genes differentially expressed following the BRD-K94012289_OSI-027_BT20_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAPG capping protein (actin filament), gelsolin-like
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CFB complement factor B
COL3A1 collagen, type III, alpha 1
CTNND1 catenin (cadherin-associated protein), delta 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EAPP E2F-associated phosphoprotein
EDNRB endothelin receptor type B
FCMR Fc fragment of IgM receptor
FN1 fibronectin 1
GNAS GNAS complex locus
GPR137B G protein-coupled receptor 137B
H2AFY H2A histone family, member Y
HBP1 HMG-box transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST2H2BE histone cluster 2, H2be
HMOX1 heme oxygenase 1
IFITM1 interferon induced transmembrane protein 1
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITGA6 integrin, alpha 6
KLF9 Kruppel-like factor 9
LBH limb bud and heart development
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC15 leucine rich repeat containing 15
LUM lumican
MDFIC MyoD family inhibitor domain containing
NDFIP1 Nedd4 family interacting protein 1
NEFH neurofilament, heavy polypeptide
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFD platelet derived growth factor D
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHJ1 pleckstrin homology domain containing, family J member 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
REG1B regenerating islet-derived 1 beta
RGCC regulator of cell cycle
RTN2 reticulon 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SEPP1 selenoprotein P, plasma, 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
THY1 Thy-1 cell surface antigen
TIMP3 TIMP metallopeptidase inhibitor 3
TM7SF2 transmembrane 7 superfamily member 2
TWIST1 twist family bHLH transcription factor 1
XIST X inactive specific transcript (non-protein coding)
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AK2 adenylate kinase 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
AMIGO2 adhesion molecule with Ig-like domain 2
ATG3 autophagy related 3
AXL AXL receptor tyrosine kinase
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA12 carbonic anhydrase XII
CDC25A cell division cycle 25A
CHPT1 choline phosphotransferase 1
CRISP3 cysteine-rich secretory protein 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
FAM57A family with sequence similarity 57, member A
FASN fatty acid synthase
GPI glucose-6-phosphate isomerase
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HSPA8 heat shock 70kDa protein 8
HSPB8 heat shock 22kDa protein 8
KRT13 keratin 13, type I
LBR lamin B receptor
LOC100505650 uncharacterized LOC100505650
MBOAT7 membrane bound O-acyltransferase domain containing 7
MMP7 matrix metallopeptidase 7
MPO myeloperoxidase
MRPL12 mitochondrial ribosomal protein L12
MYBPC1 myosin binding protein C, slow type
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPR3 natriuretic peptide receptor 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ODC1 ornithine decarboxylase 1
PCDH9 protocadherin 9
PFKP phosphofructokinase, platelet
RFC5 replication factor C (activator 1) 5, 36.5kDa
RHOB ras homolog family member B
RRM2 ribonucleotide reductase M2
S100A2 S100 calcium binding protein A2
SFN stratifin
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SNX10 sorting nexin 10
SPRR1A small proline-rich protein 1A
SRSF6 serine/arginine-rich splicing factor 6
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TPSAB1 tryptase alpha/beta 1
TSC22D1 TSC22 domain family, member 1
TYMS thymidylate synthetase