BRD-K94012289_OSI-027_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K94012289_OSI-027_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ADD3 adducin 3 (gamma)
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
BEX1 brain expressed, X-linked 1
CD44 CD44 molecule (Indian blood group)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COMP cartilage oligomeric matrix protein
CPVL carboxypeptidase, vitellogenic-like
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
DDAH1 dimethylarginine dimethylaminohydrolase 1
FXYD6 FXYD domain containing ion transport regulator 6
IFI6 interferon, alpha-inducible protein 6
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
KRT7 keratin 7, type II
MARCKS myristoylated alanine-rich protein kinase C substrate
METTL7A methyltransferase like 7A
NDRG1 N-myc downstream regulated 1
NPTX2 neuronal pentraxin II
PTN pleiotrophin
PTPRE protein tyrosine phosphatase, receptor type, E
PTX3 pentraxin 3, long
RRAGD Ras-related GTP binding D
SDC2 syndecan 2
TFF1 trefoil factor 1
TGM2 transglutaminase 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TSPAN4 tetraspanin 4
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VNN1 vanin 1

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
CPB1 carboxypeptidase B1 (tissue)
CSTA cystatin A (stefin A)
CTTN cortactin
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
EREG epiregulin
FAM129A family with sequence similarity 129, member A
FXYD3 FXYD domain containing ion transport regulator 3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IDO1 indoleamine 2,3-dioxygenase 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JCHAIN joining chain of multimeric IgA and IgM
KRT14 keratin 14, type I
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MEIS2 Meis homeobox 2
MME membrane metallo-endopeptidase
NR4A2 nuclear receptor subfamily 4, group A, member 2
PHGDH phosphoglycerate dehydrogenase
PLK2 polo-like kinase 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPRR1B small proline-rich protein 1B
SSBP2 single-stranded DNA binding protein 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPD52L1 tumor protein D52-like 1