BRD-K93788137_PF-431396_MDAMB231_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K93788137_PF-431396_MDAMB231_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CXCL2 chemokine (C-X-C motif) ligand 2
DDIT4 DNA-damage-inducible transcript 4
ESR1 estrogen receptor 1
FASTKD5 FAST kinase domains 5
KIAA0226L KIAA0226-like
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYN LYN proto-oncogene, Src family tyrosine kinase
NRIP3 nuclear receptor interacting protein 3
OSBPL8 oxysterol binding protein-like 8
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PVALB parvalbumin
RGS10 regulator of G-protein signaling 10
RGS5 regulator of G-protein signaling 5
S100P S100 calcium binding protein P
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
TCL1A T-cell leukemia/lymphoma 1A
THBD thrombomodulin
TSC22D3 TSC22 domain family, member 3
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
ATXN1 ataxin 1
AUTS2 autism susceptibility candidate 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C10ORF10 chromosome 10 open reading frame 10
C6ORF62 chromosome 6 open reading frame 62
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CELF2 CUGBP, Elav-like family member 2
CFH complement factor H
CYBRD1 cytochrome b reductase 1
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DPYSL3 dihydropyrimidinase-like 3
DUSP6 dual specificity phosphatase 6
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5 eukaryotic translation initiation factor 5
FBN1 fibrillin 1
FJX1 four jointed box 1 (Drosophila)
FLNB filamin B, beta
GATA6 GATA binding protein 6
GIMAP4 GTPase, IMAP family member 4
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HMGA2 high mobility group AT-hook 2
HOPX HOP homeobox
KDM5D lysine (K)-specific demethylase 5D
LMO4 LIM domain only 4
MACF1 microtubule-actin crosslinking factor 1
MAST4 microtubule associated serine/threonine kinase family member 4
MBNL2 muscleblind-like splicing regulator 2
MEF2C myocyte enhancer factor 2C
MMD monocyte to macrophage differentiation-associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBPF10 neuroblastoma breakpoint family, member 10
NUP62 nucleoporin 62kDa
NXN nucleoredoxin
PBX3 pre-B-cell leukemia homeobox 3
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKCH protein kinase C, eta
S100A9 S100 calcium binding protein A9
SAMD4A sterile alpha motif domain containing 4A
SMAD3 SMAD family member 3
SPON1 spondin 1, extracellular matrix protein
SULF1 sulfatase 1
TOX3 TOX high mobility group box family member 3