BRD-K93788137_PF-431396_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K93788137_PF-431396_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADO 2-aminoethanethiol (cysteamine) dioxygenase
BHLHE41 basic helix-loop-helix family, member e41
DDIT4 DNA-damage-inducible transcript 4
DTX4 deltex 4, E3 ubiquitin ligase
EHF ets homologous factor
FABP4 fatty acid binding protein 4, adipocyte
FOXO1 forkhead box O1
GDF15 growth differentiation factor 15
GFOD1 glucose-fructose oxidoreductase domain containing 1
KRT19 keratin 19, type I
LMO2 LIM domain only 2 (rhombotin-like 1)
LXN latexin
LY75 lymphocyte antigen 75
MAP7 microtubule-associated protein 7
MT1M metallothionein 1M
OLFM4 olfactomedin 4
PROM1 prominin 1
SELL selectin L
SMC1A structural maintenance of chromosomes 1A
TFF1 trefoil factor 1
TGM2 transglutaminase 2
THAP11 THAP domain containing 11
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AMOTL2 angiomotin like 2
ASPH aspartate beta-hydroxylase
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CAPN2 calpain 2, (m/II) large subunit
CAV2 caveolin 2
CLEC3B C-type lectin domain family 3, member B
COL3A1 collagen, type III, alpha 1
CREB1 cAMP responsive element binding protein 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
EDN1 endothelin 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EMP1 epithelial membrane protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
F13A1 coagulation factor XIII, A1 polypeptide
FGG fibrinogen gamma chain
GULP1 GULP, engulfment adaptor PTB domain containing 1
KDM5D lysine (K)-specific demethylase 5D
KRT23 keratin 23, type I
MATN2 matrilin 2
NRIP1 nuclear receptor interacting protein 1
PDLIM1 PDZ and LIM domain 1
PGAM1 phosphoglycerate mutase 1 (brain)
S100A2 S100 calcium binding protein A2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLIT2 slit homolog 2 (Drosophila)
SORBS2 sorbin and SH3 domain containing 2
SPP1 secreted phosphoprotein 1
STAB1 stabilin 1
STC2 stanniocalcin 2
TNC tenascin C
TSPAN7 tetraspanin 7
TUBB2A tubulin, beta 2A class IIa