BRD-K93788137_PF-431396_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K93788137_PF-431396_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
AMIGO2 adhesion molecule with Ig-like domain 2
APOD apolipoprotein D
APOLD1 apolipoprotein L domain containing 1
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BANK1 B-cell scaffold protein with ankyrin repeats 1
BLNK B-cell linker
C6ORF62 chromosome 6 open reading frame 62
CD9 CD9 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
EHD3 EH-domain containing 3
EIF5A eukaryotic translation initiation factor 5A
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FABP4 fatty acid binding protein 4, adipocyte
FOXO4 forkhead box O4
FXYD3 FXYD domain containing ion transport regulator 3
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GREM1 gremlin 1, DAN family BMP antagonist
GSN gelsolin
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
HOXB7 homeobox B7
IGL immunoglobulin lambda locus
JAG1 jagged 1
JUP junction plakoglobin
MME membrane metallo-endopeptidase
MUC1 mucin 1, cell surface associated
NR4A3 nuclear receptor subfamily 4, group A, member 3
NT5DC2 5'-nucleotidase domain containing 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PERP PERP, TP53 apoptosis effector
PIEZO2 piezo-type mechanosensitive ion channel component 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RUNX3 runt-related transcription factor 3
SH3BGRL SH3 domain binding glutamate-rich protein like
SRGN serglycin
TCF4 transcription factor 4
TNS3 tensin 3
TRIM2 tripartite motif containing 2
TSPAN7 tetraspanin 7
VDAC1 voltage-dependent anion channel 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ASRGL1 asparaginase like 1
CALD1 caldesmon 1
CD14 CD14 molecule
CD69 CD69 molecule
CLEC2B C-type lectin domain family 2, member B
CPVL carboxypeptidase, vitellogenic-like
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF3M eukaryotic translation initiation factor 3, subunit M
FAM129A family with sequence similarity 129, member A
FNBP1 formin binding protein 1
GTPBP8 GTP-binding protein 8 (putative)
IPO7 importin 7
KIF20A kinesin family member 20A
LAPTM4B lysosomal protein transmembrane 4 beta
MAOB monoamine oxidase B
NES nestin
NFIB nuclear factor I/B
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK2 polo-like kinase 2
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
RAB4A RAB4A, member RAS oncogene family
RBP1 retinol binding protein 1, cellular
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SNRPE small nuclear ribonucleoprotein polypeptide E
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SRP72 signal recognition particle 72kDa
TUBB2A tubulin, beta 2A class IIa
VCAN versican
ZIC1 Zic family member 1