BRD-K93754473_-666_SW620_6.0_h_28.39_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K93754473_-666_SW620_6.0_h_28.39_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
AMIGO2 adhesion molecule with Ig-like domain 2
APOD apolipoprotein D
ASNS asparagine synthetase (glutamine-hydrolyzing)
CD52 CD52 molecule
CLEC2B C-type lectin domain family 2, member B
COMP cartilage oligomeric matrix protein
CORO1A coronin, actin binding protein, 1A
CSTA cystatin A (stefin A)
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNM1L dynamin 1-like
EIF4A1 eukaryotic translation initiation factor 4A1
F11R F11 receptor
FADS1 fatty acid desaturase 1
FHOD3 formin homology 2 domain containing 3
GAGE3 G antigen 3
GPNMB glycoprotein (transmembrane) nmb
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
IFI16 interferon, gamma-inducible protein 16
IFNAR1 interferon (alpha, beta and omega) receptor 1
INSIG1 insulin induced gene 1
ITM2A integral membrane protein 2A
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
LGALS8 lectin, galactoside-binding, soluble, 8
MB myoglobin
MSMO1 methylsterol monooxygenase 1
MYBPC1 myosin binding protein C, slow type
NR1H2 nuclear receptor subfamily 1, group H, member 2
S100A13 S100 calcium binding protein A13
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STAR steroidogenic acute regulatory protein
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULF1 sulfatase 1
TCEAL2 transcription elongation factor A (SII)-like 2
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THBS2 thrombospondin 2
TNNT1 troponin T type 1 (skeletal, slow)
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AXIN1 axin 1
CAST calpastatin
CDC20 cell division cycle 20
CHIC2 cysteine-rich hydrophobic domain 2
CHN2 chimerin 2
COL2A1 collagen, type II, alpha 1
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DACH1 dachshund family transcription factor 1
FKBP10 FK506 binding protein 10, 65 kDa
FOLR1 folate receptor 1 (adult)
GRIA2 glutamate receptor, ionotropic, AMPA 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KAZN kazrin, periplakin interacting protein
MGP matrix Gla protein
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MT1E metallothionein 1E
NT5DC2 5'-nucleotidase domain containing 2
SERTAD2 SERTA domain containing 2
SRGN serglycin
STK39 serine threonine kinase 39
UBE2S ubiquitin-conjugating enzyme E2S