BRD-K93754473_-666_HA1E_6.0_h_28.39_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K93754473_-666_HA1E_6.0_h_28.39_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CD52 CD52 molecule
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT4 DNA-damage-inducible transcript 4
FAM13A family with sequence similarity 13, member A
FCGBP Fc fragment of IgG binding protein
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
KIAA0753 KIAA0753
MDK midkine (neurite growth-promoting factor 2)
RAB31 RAB31, member RAS oncogene family
RGS1 regulator of G-protein signaling 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
TBC1D31 TBC1 domain family, member 31
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT1 acetyl-CoA acetyltransferase 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BEX1 brain expressed, X-linked 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDC42 cell division cycle 42
DEFB1 defensin, beta 1
DICER1 dicer 1, ribonuclease type III
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
HSPB8 heat shock 22kDa protein 8
KLF6 Kruppel-like factor 6
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MICALL1 MICAL-like 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SPINK1 serine peptidase inhibitor, Kazal type 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRSF6 serine/arginine-rich splicing factor 6
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
ZBTB18 zinc finger and BTB domain containing 18