BRD-K93747373_HG-5-113-01_SKBR3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K93747373_HG-5-113-01_SKBR3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ANXA6 annexin A6
ASNS asparagine synthetase (glutamine-hydrolyzing)
CD96 CD96 molecule
CXCL5 chemokine (C-X-C motif) ligand 5
EMP3 epithelial membrane protein 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FGB fibrinogen beta chain
HSPA2 heat shock 70kDa protein 2
LBH limb bud and heart development
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MX1 MX dynamin-like GTPase 1
NELL2 NEL-like 2 (chicken)
NPTX2 neuronal pentraxin II
PRUNE2 prune homolog 2 (Drosophila)
RABAC1 Rab acceptor 1 (prenylated)
RBP1 retinol binding protein 1, cellular
RGS5 regulator of G-protein signaling 5
RRBP1 ribosome binding protein 1
RSRP1 arginine/serine-rich protein 1
SCGB1D2 secretoglobin, family 1D, member 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SMAD3 SMAD family member 3
TSTA3 tissue specific transplantation antigen P35B
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
APOD apolipoprotein D
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BASP1 brain abundant, membrane attached signal protein 1
BHLHE41 basic helix-loop-helix family, member e41
BZW2 basic leucine zipper and W2 domains 2
C3 complement component 3
CALB1 calbindin 1, 28kDa
CD47 CD47 molecule
CD58 CD58 molecule
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLDN3 claudin 3
CLIC3 chloride intracellular channel 3
COL3A1 collagen, type III, alpha 1
DHCR24 24-dehydrocholesterol reductase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
FOLR1 folate receptor 1 (adult)
FPGS folylpolyglutamate synthase
GALE UDP-galactose-4-epimerase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
LAMP2 lysosomal-associated membrane protein 2
LCN2 lipocalin 2
LTBP1 latent transforming growth factor beta binding protein 1
MET MET proto-oncogene, receptor tyrosine kinase
MME membrane metallo-endopeptidase
MPZL2 myelin protein zero-like 2
MREG melanoregulin
MYB v-myb avian myeloblastosis viral oncogene homolog
NOTCH2 notch 2
NXN nucleoredoxin
PCCB propionyl CoA carboxylase, beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PXDN peroxidasin
RRM2 ribonucleotide reductase M2
SC5D sterol-C5-desaturase
SFN stratifin
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SST somatostatin
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)