BRD-K93747373_HG-5-113-01_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K93747373_HG-5-113-01_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEPTOR DEP domain containing MTOR-interacting protein
DPP4 dipeptidyl-peptidase 4
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ESR1 estrogen receptor 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM171A1 family with sequence similarity 171, member A1
FAS Fas cell surface death receptor
FLRT2 fibronectin leucine rich transmembrane protein 2
FSD1 fibronectin type III and SPRY domain containing 1
GAS1 growth arrest-specific 1
GZMK granzyme K (granzyme 3; tryptase II)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BK histone cluster 1, H2bk
HOXB2 homeobox B2
ITM2A integral membrane protein 2A
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM5D lysine (K)-specific demethylase 5D
LAMC1 laminin, gamma 1 (formerly LAMB2)
LRRC17 leucine rich repeat containing 17
MEIS1 Meis homeobox 1
MUC16 mucin 16, cell surface associated
NAV3 neuron navigator 3
NDRG1 N-myc downstream regulated 1
NEFH neurofilament, heavy polypeptide
NID2 nidogen 2 (osteonidogen)
NPTX1 neuronal pentraxin I
PVALB parvalbumin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
SCGB2A1 secretoglobin, family 2A, member 1
SDC4 syndecan 4
SFRP1 secreted frizzled-related protein 1
SNAP25 synaptosomal-associated protein, 25kDa
SOX17 SRY (sex determining region Y)-box 17
SPON1 spondin 1, extracellular matrix protein
TFPI2 tissue factor pathway inhibitor 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TM4SF1 transmembrane 4 L six family member 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRAT1 T cell receptor associated transmembrane adaptor 1
VCAM1 vascular cell adhesion molecule 1
WFDC2 WAP four-disulfide core domain 2
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
CAST calpastatin
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CRABP2 cellular retinoic acid binding protein 2
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DKK1 dickkopf WNT signaling pathway inhibitor 1
FERMT1 fermitin family member 1
IGFBP5 insulin-like growth factor binding protein 5
KRT20 keratin 20, type I
KRT6B keratin 6B, type II
LPL lipoprotein lipase
MALL mal, T-cell differentiation protein-like
MGP matrix Gla protein
NES nestin
NT5DC2 5'-nucleotidase domain containing 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
SDC1 syndecan 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SOX9 SRY (sex determining region Y)-box 9
TBX2 T-box 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)