BRD-K93747373_HG-5-113-01_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K93747373_HG-5-113-01_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
CCNA1 cyclin A1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDIT4 DNA-damage-inducible transcript 4
DENND2D DENN/MADD domain containing 2D
DUSP5 dual specificity phosphatase 5
F13A1 coagulation factor XIII, A1 polypeptide
HBB hemoglobin, beta
IGL immunoglobulin lambda locus
NDRG1 N-myc downstream regulated 1
NPTX2 neuronal pentraxin II
PAM peptidylglycine alpha-amidating monooxygenase
PLIN2 perilipin 2
RBM8A RNA binding motif protein 8A
RHOB ras homolog family member B
SH3YL1 SH3 and SYLF domain containing 1
SPON2 spondin 2, extracellular matrix protein
TFF3 trefoil factor 3 (intestinal)

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
ATAD2 ATPase family, AAA domain containing 2
CCNE2 cyclin E2
CDC6 cell division cycle 6
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EFNB2 ephrin-B2
FGFR3 fibroblast growth factor receptor 3
GINS2 GINS complex subunit 2 (Psf2 homolog)
GOLT1B golgi transport 1B
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
MCM10 minichromosome maintenance complex component 10
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PSIP1 PC4 and SFRS1 interacting protein 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RANBP1 RAN binding protein 1
RFC2 replication factor C (activator 1) 2, 40kDa
RRM2 ribonucleotide reductase M2
SERINC5 serine incorporator 5
SLC39A8 solute carrier family 39 (zinc transporter), member 8