BRD-K93747373_HG-5-113-01_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K93747373_HG-5-113-01_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANKRD10 ankyrin repeat domain 10
CCL8 chemokine (C-C motif) ligand 8
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CPE carboxypeptidase E
CRABP1 cellular retinoic acid binding protein 1
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL11 chemokine (C-X-C motif) ligand 11
DUSP6 dual specificity phosphatase 6
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
GLI2 GLI family zinc finger 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GOLGA8A golgin A8 family, member A
GPC3 glypican 3
GPX1 glutathione peroxidase 1
HNMT histamine N-methyltransferase
IDO1 indoleamine 2,3-dioxygenase 1
IFI44L interferon-induced protein 44-like
IGFBP5 insulin-like growth factor binding protein 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITM2A integral membrane protein 2A
LYN LYN proto-oncogene, Src family tyrosine kinase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MEF2C myocyte enhancer factor 2C
NRN1 neuritin 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEG3 paternally expressed 3
PHYH phytanoyl-CoA 2-hydroxylase
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PTN pleiotrophin
PTPRC protein tyrosine phosphatase, receptor type, C
RSAD2 radical S-adenosyl methionine domain containing 2
S100P S100 calcium binding protein P
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SPP1 secreted phosphoprotein 1
SRPX sushi-repeat containing protein, X-linked
SSPN sarcospan
TLE4 transducin-like enhancer of split 4
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TOX3 TOX high mobility group box family member 3
TSPAN8 tetraspanin 8
VAV3 vav 3 guanine nucleotide exchange factor
VLDLR very low density lipoprotein receptor

decreased expression

Symbol Name
ADCK3 aarF domain containing kinase 3
ADD3 adducin 3 (gamma)
AIM1 absent in melanoma 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
GLUL glutamate-ammonia ligase
KRT18 keratin 18, type I
LITAF lipopolysaccharide-induced TNF factor
NAMPT nicotinamide phosphoribosyltransferase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
SNAP25 synaptosomal-associated protein, 25kDa
SYT1 synaptotagmin I
TACSTD2 tumor-associated calcium signal transducer 2
TBP TATA box binding protein