BRD-K93747373_HG-5-113-01_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K93747373_HG-5-113-01_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
ANXA1 annexin A1
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRABP2 cellular retinoic acid binding protein 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DUSP1 dual specificity phosphatase 1
EIF5A eukaryotic translation initiation factor 5A
FRY furry homolog (Drosophila)
FRZB frizzled-related protein
GAS6 growth arrest-specific 6
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BD histone cluster 1, H2bd
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
ISG15 ISG15 ubiquitin-like modifier
KRT19 keratin 19, type I
MAGED2 melanoma antigen family D2
MMP7 matrix metallopeptidase 7
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
NEBL nebulette
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PBX1 pre-B-cell leukemia homeobox 1
PDZD2 PDZ domain containing 2
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
RSAD2 radical S-adenosyl methionine domain containing 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TBX2 T-box 2
TNNT1 troponin T type 1 (skeletal, slow)

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
CCNA2 cyclin A2
CENPN centromere protein N
CENPU centromere protein U
CLCA4 chloride channel accessory 4
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COMMD8 COMM domain containing 8
CREB1 cAMP responsive element binding protein 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EVI2A ecotropic viral integration site 2A
F13A1 coagulation factor XIII, A1 polypeptide
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GAP43 growth associated protein 43
GPER1 G protein-coupled estrogen receptor 1
HNMT histamine N-methyltransferase
IGFBP5 insulin-like growth factor binding protein 5
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0226L KIAA0226-like
KIF14 kinesin family member 14
KLK11 kallikrein-related peptidase 11
LDHB lactate dehydrogenase B
LMO3 LIM domain only 3 (rhombotin-like 2)
LPPR1 lipid phosphate phosphatase-related protein type 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAN1A1 mannosidase, alpha, class 1A, member 1
MCTP1 multiple C2 domains, transmembrane 1
MKI67 marker of proliferation Ki-67
NEK2 NIMA-related kinase 2
PCP4 Purkinje cell protein 4
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBM3 RNA binding motif (RNP1, RRM) protein 3
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SNAP25 synaptosomal-associated protein, 25kDa
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SULF1 sulfatase 1
TGFBI transforming growth factor, beta-induced, 68kDa
TPD52L1 tumor protein D52-like 1
VAMP8 vesicle-associated membrane protein 8
VSNL1 visinin-like 1
ZBTB18 zinc finger and BTB domain containing 18