BRD-K93658967_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K93658967_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CDK19 cyclin-dependent kinase 19
CXCL13 chemokine (C-X-C motif) ligand 13
DDR1 discoidin domain receptor tyrosine kinase 1
DUSP4 dual specificity phosphatase 4
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
IGFBP6 insulin-like growth factor binding protein 6
IL7R interleukin 7 receptor
IRS2 insulin receptor substrate 2
KRT19 keratin 19, type I
LTF lactotransferrin
MAP7 microtubule-associated protein 7
MBP myelin basic protein
NLGN4X neuroligin 4, X-linked
OLFM1 olfactomedin 1
PDZK1 PDZ domain containing 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PTGES prostaglandin E synthase
PYCARD PYD and CARD domain containing
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
TAGLN transgelin
TARP TCR gamma alternate reading frame protein

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADGRF5 adhesion G protein-coupled receptor F5
ARMCX6 armadillo repeat containing, X-linked 6
ATF5 activating transcription factor 5
CAST calpastatin
CEP57 centrosomal protein 57kDa
CXADR coxsackie virus and adenovirus receptor
DLC1 DLC1 Rho GTPase activating protein
FN1 fibronectin 1
GDF15 growth differentiation factor 15
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IFI6 interferon, alpha-inducible protein 6
IGFBP5 insulin-like growth factor binding protein 5
KYNU kynureninase
LGALS3 lectin, galactoside-binding, soluble, 3
LMO2 LIM domain only 2 (rhombotin-like 1)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
METTL7A methyltransferase like 7A
MT1F metallothionein 1F
MT1X metallothionein 1X
PCDH9 protocadherin 9
PDE8B phosphodiesterase 8B
PLBD1 phospholipase B domain containing 1
RGS5 regulator of G-protein signaling 5
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
TEX10 testis expressed 10
TUSC3 tumor suppressor candidate 3