BRD-K93658967_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K93658967_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASS1 argininosuccinate synthase 1
COL3A1 collagen, type III, alpha 1
DUSP4 dual specificity phosphatase 4
LYZ lysozyme
NEB nebulin
PSAP prosaposin
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SHB Src homology 2 domain containing adaptor protein B
TIMP3 TIMP metallopeptidase inhibitor 3

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
AXL AXL receptor tyrosine kinase
CPM carboxypeptidase M
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL12 chemokine (C-X-C motif) ligand 12
IRS2 insulin receptor substrate 2
KIF23 kinesin family member 23
LDLR low density lipoprotein receptor
MOK MOK protein kinase
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDLIM5 PDZ and LIM domain 5
PODXL podocalyxin-like
PTX3 pentraxin 3, long
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SMAD3 SMAD family member 3
SMS spermine synthase
STOM stomatin
SYNE1 spectrin repeat containing, nuclear envelope 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR3 transforming growth factor, beta receptor III
TNS3 tensin 3
TPM1 tropomyosin 1 (alpha)
TSPAN8 tetraspanin 8
ZDHHC6 zinc finger, DHHC-type containing 6