BRD-K93623501_NCGC00186101-01_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K93623501_NCGC00186101-01_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ARHGAP6 Rho GTPase activating protein 6
ATP10B ATPase, class V, type 10B
BAG2 BCL2-associated athanogene 2
CCL19 chemokine (C-C motif) ligand 19
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
EMP1 epithelial membrane protein 1
G6PD glucose-6-phosphate dehydrogenase
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HMOX1 heme oxygenase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAOA monoamine oxidase A
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSMB microseminoprotein, beta-
MT1E metallothionein 1E
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MUC4 mucin 4, cell surface associated
MX2 MX dynamin-like GTPase 2
NQO1 NAD(P)H dehydrogenase, quinone 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PER2 period circadian clock 2
PGD phosphogluconate dehydrogenase
PRAME preferentially expressed antigen in melanoma
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SCG2 secretogranin II
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TKT transketolase
TRIM2 tripartite motif containing 2
TSKU tsukushi, small leucine rich proteoglycan
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ANXA3 annexin A3
AUTS2 autism susceptibility candidate 2
CCL5 chemokine (C-C motif) ligand 5
CKLF chemokine-like factor
CPB1 carboxypeptidase B1 (tissue)
CST7 cystatin F (leukocystatin)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DSP desmoplakin
EDNRB endothelin receptor type B
GOLT1B golgi transport 1B
KIF20A kinesin family member 20A
KRT19 keratin 19, type I
LPL lipoprotein lipase
MCTP1 multiple C2 domains, transmembrane 1
NKG7 natural killer cell granule protein 7
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PROM1 prominin 1
RGS1 regulator of G-protein signaling 1
SDC2 syndecan 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SPON2 spondin 2, extracellular matrix protein
TSPAN13 tetraspanin 13
ZNF586 zinc finger protein 586