BRD-K93578426_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K93578426_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ANXA4 annexin A4
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CARS cysteinyl-tRNA synthetase
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CRABP2 cellular retinoic acid binding protein 2
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
DUOX2 dual oxidase 2
EYA1 EYA transcriptional coactivator and phosphatase 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM13A family with sequence similarity 13, member A
FCGBP Fc fragment of IgG binding protein
GLRX glutaredoxin (thioltransferase)
GPX2 glutathione peroxidase 2
HBB hemoglobin, beta
HK2 hexokinase 2
HMOX1 heme oxygenase 1
IER3 immediate early response 3
ITM2C integral membrane protein 2C
LMO3 LIM domain only 3 (rhombotin-like 2)
LXN latexin
LYZ lysozyme
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
PTGIS prostaglandin I2 (prostacyclin) synthase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SELENBP1 selenium binding protein 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC16A4 solute carrier family 16, member 4
SOCS1 suppressor of cytokine signaling 1
SOX9 SRY (sex determining region Y)-box 9
SPON2 spondin 2, extracellular matrix protein
SYT1 synaptotagmin I
TGFBI transforming growth factor, beta-induced, 68kDa
TRIB3 tribbles pseudokinase 3

decreased expression

Symbol Name
ANKRD10 ankyrin repeat domain 10
APOD apolipoprotein D
ATF5 activating transcription factor 5
BASP1 brain abundant, membrane attached signal protein 1
CA2 carbonic anhydrase II
CCNE2 cyclin E2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
FAM46A family with sequence similarity 46, member A
ITM2A integral membrane protein 2A
KCTD12 potassium channel tetramerization domain containing 12
KIF14 kinesin family member 14
NFIB nuclear factor I/B
PDGFA platelet-derived growth factor alpha polypeptide
PPIF peptidylprolyl isomerase F
RDX radixin
SAC3D1 SAC3 domain containing 1
SLPI secretory leukocyte peptidase inhibitor
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)