BRD-K93296644_-666_NPC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

130 genes differentially expressed following the BRD-K93296644_-666_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
ACOT13 acyl-CoA thioesterase 13
ACP5 acid phosphatase 5, tartrate resistant
AIM1 absent in melanoma 1
ANXA4 annexin A4
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL4C ADP-ribosylation factor-like 4C
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLNK B-cell linker
C10ORF10 chromosome 10 open reading frame 10
C6ORF62 chromosome 6 open reading frame 62
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCNB2 cyclin B2
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC25B cell division cycle 25B
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
COG7 component of oligomeric golgi complex 7
COL8A2 collagen, type VIII, alpha 2
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CTNND1 catenin (cadherin-associated protein), delta 1
DEFA4 defensin, alpha 4, corticostatin
DENND1B DENN/MADD domain containing 1B
DNTT DNA nucleotidylexotransferase
EPAS1 endothelial PAS domain protein 1
EPCAM epithelial cell adhesion molecule
FAM69A family with sequence similarity 69, member A
FGFR2 fibroblast growth factor receptor 2
GAS6 growth arrest-specific 6
GATA3 GATA binding protein 3
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
GUSBP11 glucuronidase, beta pseudogene 11
HIST1H2BG histone cluster 1, H2bg
HOMER3 homer scaffolding protein 3
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IFIH1 interferon induced with helicase C domain 1
IGL immunoglobulin lambda locus
IGLL1 immunoglobulin lambda-like polypeptide 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL13RA1 interleukin 13 receptor, alpha 1
IPO13 importin 13
ITGB4 integrin, beta 4
JCHAIN joining chain of multimeric IgA and IgM
KCTD12 potassium channel tetramerization domain containing 12
LITAF lipopolysaccharide-induced TNF factor
MAN1A1 mannosidase, alpha, class 1A, member 1
MMP9 matrix metallopeptidase 9
PECAM1 platelet/endothelial cell adhesion molecule 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
POSTN periostin, osteoblast specific factor
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTK2B protein tyrosine kinase 2 beta
PTPRK protein tyrosine phosphatase, receptor type, K
PXN paxillin
PYCARD PYD and CARD domain containing
RAB25 RAB25, member RAS oncogene family
RGCC regulator of cell cycle
RIMS3 regulating synaptic membrane exocytosis 3
S100A8 S100 calcium binding protein A8
SDC1 syndecan 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SHB Src homology 2 domain containing adaptor protein B
SKAP2 src kinase associated phosphoprotein 2
SOCS2 suppressor of cytokine signaling 2
SOWAHC sosondowah ankyrin repeat domain family member C
SQRDL sulfide quinone reductase-like (yeast)
THBS1 thrombospondin 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIB3 tribbles pseudokinase 3
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF331 zinc finger protein 331
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGR2 anterior gradient 2
AKAP12 A kinase (PRKA) anchor protein 12
ALCAM activated leukocyte cell adhesion molecule
ANXA5 annexin A5
APOD apolipoprotein D
BST2 bone marrow stromal cell antigen 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLU clusterin
CTGF connective tissue growth factor
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DCBLD2 discoidin, CUB and LCCL domain containing 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
EGR3 early growth response 3
F13A1 coagulation factor XIII, A1 polypeptide
GOLGA8A golgin A8 family, member A
GSTA4 glutathione S-transferase alpha 4
GSTM3 glutathione S-transferase mu 3 (brain)
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
KPNB1 karyopherin (importin) beta 1
KRT10 keratin 10, type I
LAMC1 laminin, gamma 1 (formerly LAMB2)
LPAR1 lysophosphatidic acid receptor 1
LRP4 low density lipoprotein receptor-related protein 4
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEIS1 Meis homeobox 1
NDN necdin, melanoma antigen (MAGE) family member
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PCDH9 protocadherin 9
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PNMA1 paraneoplastic Ma antigen 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PROM1 prominin 1
PTCH1 patched 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RPS11 ribosomal protein S11
SACS sacsin molecular chaperone
SET SET nuclear proto-oncogene
SRSF6 serine/arginine-rich splicing factor 6
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TUBB2B tubulin, beta 2B class IIb