BRD-K93215584_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K93215584_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
BTG1 B-cell translocation gene 1, anti-proliferative
CD24 CD24 molecule
CLCA4 chloride channel accessory 4
CRABP2 cellular retinoic acid binding protein 2
CYB5A cytochrome b5 type A (microsomal)
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
DUSP4 dual specificity phosphatase 4
EPS8 epidermal growth factor receptor pathway substrate 8
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FHL1 four and a half LIM domains 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNMT histamine N-methyltransferase
IFT57 intraflagellar transport 57
INSIG1 insulin induced gene 1
KLF4 Kruppel-like factor 4 (gut)
LDLR low density lipoprotein receptor
MEF2C myocyte enhancer factor 2C
MSMO1 methylsterol monooxygenase 1
MTSS1 metastasis suppressor 1
MYOF myoferlin
RHOB ras homolog family member B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPON1 spondin 1, extracellular matrix protein
SQLE squalene epoxidase
TFF3 trefoil factor 3 (intestinal)
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIB3 tribbles pseudokinase 3

decreased expression

Symbol Name
CTSC cathepsin C
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
PDGFA platelet-derived growth factor alpha polypeptide
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS4 regulator of G-protein signaling 4
SCG5 secretogranin V
SRSF6 serine/arginine-rich splicing factor 6