BRD-K93215584_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

135 genes differentially expressed following the BRD-K93215584_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADA adenosine deaminase
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALOX5 arachidonate 5-lipoxygenase
APOD apolipoprotein D
ARL4C ADP-ribosylation factor-like 4C
BLNK B-cell linker
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CCNE2 cyclin E2
CD14 CD14 molecule
CD163 CD163 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD52 CD52 molecule
CD99 CD99 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC5A C-type lectin domain family 5, member A
COL15A1 collagen, type XV, alpha 1
CPE carboxypeptidase E
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPAS1 endothelial PAS domain protein 1
ERBB4 erb-b2 receptor tyrosine kinase 4
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FAM49A family with sequence similarity 49, member A
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
FRY furry homolog (Drosophila)
FTH1 ferritin, heavy polypeptide 1
GLUL glutamate-ammonia ligase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IGFBP5 insulin-like growth factor binding protein 5
JADE3 jade family PHD finger 3
JCHAIN joining chain of multimeric IgA and IgM
KLF11 Kruppel-like factor 11
LMO3 LIM domain only 3 (rhombotin-like 2)
LY96 lymphocyte antigen 96
LYZ lysozyme
MAN1A1 mannosidase, alpha, class 1A, member 1
MYO1D myosin ID
MZB1 marginal zone B and B1 cell-specific protein
NCF2 neutrophil cytosolic factor 2
PHIP pleckstrin homology domain interacting protein
PLIN2 perilipin 2
PLVAP plasmalemma vesicle associated protein
RGS5 regulator of G-protein signaling 5
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPARCL1 SPARC-like 1 (hevin)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TCF4 transcription factor 4
TMEM30B transmembrane protein 30B
TNS1 tensin 1
TYROBP TYRO protein tyrosine kinase binding protein
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VGLL1 vestigial-like family member 1
VSIG4 V-set and immunoglobulin domain containing 4
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)
ZNF107 zinc finger protein 107
ZNF117 zinc finger protein 117

decreased expression

Symbol Name
ACLY ATP citrate lyase
ACSL5 acyl-CoA synthetase long-chain family member 5
ALCAM activated leukocyte cell adhesion molecule
AMD1 adenosylmethionine decarboxylase 1
ANXA3 annexin A3
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BAG1 BCL2-associated athanogene
CCND1 cyclin D1
CDC42 cell division cycle 42
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHL1 cell adhesion molecule L1-like
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CSE1L CSE1 chromosome segregation 1-like (yeast)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLC1 DLC1 Rho GTPase activating protein
ECI2 enoyl-CoA delta isomerase 2
EHD1 EH-domain containing 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FOLR1 folate receptor 1 (adult)
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HSPA8 heat shock 70kDa protein 8
IFRD2 interferon-related developmental regulator 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
LIF leukemia inhibitory factor
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MARCKS myristoylated alanine-rich protein kinase C substrate
MTA1 metastasis associated 1
MYO6 myosin VI
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NUP98 nucleoporin 98kDa
PFKP phosphofructokinase, platelet
PLAC8 placenta-specific 8
PMEPA1 prostate transmembrane protein, androgen induced 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTDSS1 phosphatidylserine synthase 1
RPS11 ribosomal protein S11
S100A2 S100 calcium binding protein A2
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEPT11 septin 11
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLIRP SRA stem-loop interacting RNA binding protein
SMAD2 SMAD family member 2
SORD sorbitol dehydrogenase
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TMEM2 transmembrane protein 2
TNC tenascin C
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2S ubiquitin-conjugating enzyme E2S
UGCG UDP-glucose ceramide glucosyltransferase
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
ZBTB18 zinc finger and BTB domain containing 18
ZBTB38 zinc finger and BTB domain containing 38
ZNF586 zinc finger protein 586