BRD-K93127801_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K93127801_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADM adrenomedullin
AIM2 absent in melanoma 2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDOC aldolase C, fructose-bisphosphate
BST2 bone marrow stromal cell antigen 2
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD163 CD163 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CORO1A coronin, actin binding protein, 1A
CP ceruloplasmin (ferroxidase)
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GAS1 growth arrest-specific 1
GLRX glutaredoxin (thioltransferase)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGSF3 immunoglobulin superfamily, member 3
IL32 interleukin 32
JUNB jun B proto-oncogene
KRT17 keratin 17, type I
KRT19 keratin 19, type I
KRT81 keratin 81, type II
LGALS1 lectin, galactoside-binding, soluble, 1
LYPD3 LY6/PLAUR domain containing 3
MSX1 msh homeobox 1
PCOLCE procollagen C-endopeptidase enhancer
PLIN2 perilipin 2
PYGL phosphorylase, glycogen, liver
RBP4 retinol binding protein 4, plasma
RTN2 reticulon 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SPON1 spondin 1, extracellular matrix protein
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TFPI2 tissue factor pathway inhibitor 2
TMEM45A transmembrane protein 45A
TSKU tsukushi, small leucine rich proteoglycan
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VSIG4 V-set and immunoglobulin domain containing 4
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
CKS2 CDC28 protein kinase regulatory subunit 2
CXCL9 chemokine (C-X-C motif) ligand 9
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IRS2 insulin receptor substrate 2
PPIF peptidylprolyl isomerase F
TRIM8 tripartite motif containing 8
TSPYL5 TSPY-like 5