BRD-K93060291_TL_HRAS24 BRD-K93060291_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

45 genes differentially expressed following the BRD-K93060291_TL_HRAS24 BRD-K93060291_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHI3L2 chitinase 3-like 2
CST3 cystatin C
DHCR7 7-dehydrocholesterol reductase
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FABP7 fatty acid binding protein 7, brain
FADS1 fatty acid desaturase 1
FDPS farnesyl diphosphate synthase
FOXO4 forkhead box O4
GLRX glutaredoxin (thioltransferase)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LMO2 LIM domain only 2 (rhombotin-like 1)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
PLA2G16 phospholipase A2, group XVI
PRAME preferentially expressed antigen in melanoma
QPCT glutaminyl-peptide cyclotransferase
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQLE squalene epoxidase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGM2 transglutaminase 2
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
ASPN asporin
CPA3 carboxypeptidase A3 (mast cell)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
FGFR3 fibroblast growth factor receptor 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
MECOM MDS1 and EVI1 complex locus
PBX3 pre-B-cell leukemia homeobox 3
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen