BRD-K93034159_2-chloro-2-deoxyadenosine_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K93034159_2-chloro-2-deoxyadenosine_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ASPN asporin
ATF3 activating transcription factor 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BIRC3 baculoviral IAP repeat containing 3
BRCA1 breast cancer 1, early onset
CCL2 chemokine (C-C motif) ligand 2
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CLEC3B C-type lectin domain family 3, member B
CLU clusterin
COL14A1 collagen, type XIV, alpha 1
CXADR coxsackie virus and adenovirus receptor
DDB2 damage-specific DNA binding protein 2, 48kDa
DEFB1 defensin, beta 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FCGBP Fc fragment of IgG binding protein
FHL1 four and a half LIM domains 1
GAS7 growth arrest-specific 7
GLA galactosidase, alpha
HES1 hes family bHLH transcription factor 1
HSPB8 heat shock 22kDa protein 8
IL17RB interleukin 17 receptor B
INPP1 inositol polyphosphate-1-phosphatase
JAG1 jagged 1
KLF4 Kruppel-like factor 4 (gut)
LIG1 ligase I, DNA, ATP-dependent
LRRC17 leucine rich repeat containing 17
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MT1X metallothionein 1X
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NFIB nuclear factor I/B
PALLD palladin, cytoskeletal associated protein
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PYCARD PYD and CARD domain containing
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SDC4 syndecan 4
SPINK1 serine peptidase inhibitor, Kazal type 1
STAB1 stabilin 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN4 tetraspanin 4
WDTC1 WD and tetratricopeptide repeats 1
WEE1 WEE1 G2 checkpoint kinase

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
CCNA2 cyclin A2
CDC20 cell division cycle 20
CENPE centromere protein E, 312kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CUX1 cut-like homeobox 1
DHCR7 7-dehydrocholesterol reductase
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
G0S2 G0/G1 switch 2
H2BFS H2B histone family, member S (pseudogene)
HIST1H2AC histone cluster 1, H2ac
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LOXL1 lysyl oxidase-like 1
LYZ lysozyme
MAGEA3 melanoma antigen family A3
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7 microtubule-associated protein 7
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
PRC1 protein regulator of cytokinesis 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RHOBTB3 Rho-related BTB domain containing 3
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SCD stearoyl-CoA desaturase (delta-9-desaturase)