BRD-K92981876_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K92981876_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
C14ORF132 chromosome 14 open reading frame 132
CFB complement factor B
COBLL1 cordon-bleu WH2 repeat protein-like 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DKFZP586I1420 uncharacterized protein DKFZp586I1420
EDNRB endothelin receptor type B
ERBB4 erb-b2 receptor tyrosine kinase 4
FOXA2 forkhead box A2
GAS2 growth arrest-specific 2
GPX3 glutathione peroxidase 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
KIAA0226L KIAA0226-like
KIAA0485 uncharacterized LOC57235
MATN2 matrilin 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
OBSL1 obscurin-like 1
OXTR oxytocin receptor
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PLXNB2 plexin B2
PRUNE2 prune homolog 2 (Drosophila)
PXDN peroxidasin
REEP1 receptor accessory protein 1
SCRG1 stimulator of chondrogenesis 1
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SOX11 SRY (sex determining region Y)-box 11
SPON1 spondin 1, extracellular matrix protein
SRC SRC proto-oncogene, non-receptor tyrosine kinase
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
USP6NL USP6 N-terminal like
ZBTB20 zinc finger and BTB domain containing 20
ZDHHC11 zinc finger, DHHC-type containing 11
ZIC1 Zic family member 1

decreased expression

Symbol Name
ADM adrenomedullin
ADORA2B adenosine A2b receptor
BIK BCL2-interacting killer (apoptosis-inducing)
CD24 CD24 molecule
CD9 CD9 molecule
CDC42 cell division cycle 42
CHIC2 cysteine-rich hydrophobic domain 2
CHSY1 chondroitin sulfate synthase 1
CLEC11A C-type lectin domain family 11, member A
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP6 dual specificity phosphatase 6
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNB2 ephrin-B2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPCAM epithelial cell adhesion molecule
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FOSL1 FOS-like antigen 1
GSTM3 glutathione S-transferase mu 3 (brain)
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER3 immediate early response 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL7R interleukin 7 receptor
ITGA6 integrin, alpha 6
JAM3 junctional adhesion molecule 3
KRT19 keratin 19, type I
LCN2 lipocalin 2
LYZ lysozyme
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEX3C mex-3 RNA binding family member C
MGAM maltase-glucoamylase
MMD monocyte to macrophage differentiation-associated
OAT ornithine aminotransferase
PALLD palladin, cytoskeletal associated protein
PLS3 plastin 3
RCAN1 regulator of calcineurin 1
RGCC regulator of cell cycle
S100A2 S100 calcium binding protein A2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TACSTD2 tumor-associated calcium signal transducer 2
ZNF586 zinc finger protein 586