BRD-K92571446_WZ-3105_MDAMB231_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K92571446_WZ-3105_MDAMB231_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
APOC1 apolipoprotein C-I
APOE apolipoprotein E
CADM1 cell adhesion molecule 1
CCL19 chemokine (C-C motif) ligand 19
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CPA3 carboxypeptidase A3 (mast cell)
CXADR coxsackie virus and adenovirus receptor
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FBLN1 fibulin 1
FGFR3 fibroblast growth factor receptor 3
GATA3 GATA binding protein 3
GPM6B glycoprotein M6B
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
INA internexin neuronal intermediate filament protein, alpha
ITM2A integral membrane protein 2A
JUNB jun B proto-oncogene
OLFM1 olfactomedin 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PFKL phosphofructokinase, liver
RTN1 reticulon 1
SFTPC surfactant protein C
SPP1 secreted phosphoprotein 1
TMEM30B transmembrane protein 30B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN7 tetraspanin 7
TUSC3 tumor suppressor candidate 3
ZIC1 Zic family member 1
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADORA2B adenosine A2b receptor
ANPEP alanyl (membrane) aminopeptidase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CBR3 carbonyl reductase 3
CCNF cyclin F
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
E2F2 E2F transcription factor 2
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
GAS1 growth arrest-specific 1
GSAP gamma-secretase activating protein
HMGA2 high mobility group AT-hook 2
IFITM1 interferon induced transmembrane protein 1
IRS2 insulin receptor substrate 2
JADE2 jade family PHD finger 2
JMJD6 jumonji domain containing 6
LY6E lymphocyte antigen 6 complex, locus E
NOTCH2 notch 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PER2 period circadian clock 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIP prolactin-induced protein
PRUNE2 prune homolog 2 (Drosophila)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SMAD3 SMAD family member 3
STX1A syntaxin 1A (brain)
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)