BRD-K92571446_WZ-3105_MDAMB231_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K92571446_WZ-3105_MDAMB231_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AQP1 aquaporin 1 (Colton blood group)
CD4 CD4 molecule
CLEC7A C-type lectin domain family 7, member A
COL11A1 collagen, type XI, alpha 1
CSTA cystatin A (stefin A)
EGFL6 EGF-like-domain, multiple 6
EGR1 early growth response 1
EPCAM epithelial cell adhesion molecule
FAS Fas cell surface death receptor
FBLN1 fibulin 1
FMO2 flavin containing monooxygenase 2 (non-functional)
FOLR1 folate receptor 1 (adult)
MMP19 matrix metallopeptidase 19
MRC2 mannose receptor, C type 2
NCF2 neutrophil cytosolic factor 2
PRSS21 protease, serine, 21 (testisin)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SFRP4 secreted frizzled-related protein 4
SH3BGRL SH3 domain binding glutamate-rich protein like
SNN stannin
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TTC3 tetratricopeptide repeat domain 3
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CCNA2 cyclin A2
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CSE1L CSE1 chromosome segregation 1-like (yeast)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FOSL1 FOS-like antigen 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MGP matrix Gla protein
PCNA proliferating cell nuclear antigen
PLAC8 placenta-specific 8
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PTX3 pentraxin 3, long
RRM2 ribonucleotide reductase M2
S100P S100 calcium binding protein P
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
STOM stomatin
TACC2 transforming, acidic coiled-coil containing protein 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TM4SF1 transmembrane 4 L six family member 1
TNPO1 transportin 1
TRAPPC3 trafficking protein particle complex 3
TUBB4B tubulin, beta 4B class IVb
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
ZDHHC6 zinc finger, DHHC-type containing 6