BRD-K92571446_WZ-3105_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

102 genes differentially expressed following the BRD-K92571446_WZ-3105_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADIRF adipogenesis regulatory factor
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANPEP alanyl (membrane) aminopeptidase
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CADM1 cell adhesion molecule 1
CCL2 chemokine (C-C motif) ligand 2
CCL8 chemokine (C-C motif) ligand 8
CD14 CD14 molecule
CD163 CD163 molecule
CD59 CD59 molecule, complement regulatory protein
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD9 CD9 molecule
CD93 CD93 molecule
COTL1 coactosin-like F-actin binding protein 1
CSRP2 cysteine and glycine-rich protein 2
CTSZ cathepsin Z
CXCL9 chemokine (C-X-C motif) ligand 9
CYR61 cysteine-rich, angiogenic inducer, 61
DSP desmoplakin
EXPH5 exophilin 5
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FZD7 frizzled class receptor 7
GADD45A growth arrest and DNA-damage-inducible, alpha
GPM6B glycoprotein M6B
GPX1 glutathione peroxidase 1
GPX3 glutathione peroxidase 3
HCLS1 hematopoietic cell-specific Lyn substrate 1
HES1 hes family bHLH transcription factor 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
JUP junction plakoglobin
KIF5C kinesin family member 5C
KLHL24 kelch-like family member 24
KRT14 keratin 14, type I
LDHB lactate dehydrogenase B
LYN LYN proto-oncogene, Src family tyrosine kinase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAOA monoamine oxidase A
MFAP5 microfibrillar associated protein 5
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1M metallothionein 1M
NPTX2 neuronal pentraxin II
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUAK1 NUAK family, SNF1-like kinase, 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PECAM1 platelet/endothelial cell adhesion molecule 1
PERP PERP, TP53 apoptosis effector
PLVAP plasmalemma vesicle associated protein
RTN1 reticulon 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SNX11 sorting nexin 11
SOD2 superoxide dismutase 2, mitochondrial
SORBS1 sorbin and SH3 domain containing 1
SPARCL1 SPARC-like 1 (hevin)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SST somatostatin
TGM2 transglutaminase 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRA2A transformer 2 alpha homolog (Drosophila)
TYROBP TYRO protein tyrosine kinase binding protein
VAMP8 vesicle-associated membrane protein 8
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
CCNA2 cyclin A2
EFS embryonal Fyn-associated substrate
FGFR2 fibroblast growth factor receptor 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA8 heat shock 70kDa protein 8
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KIAA0101 KIAA0101
MAGED1 melanoma antigen family D1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NRIP1 nuclear receptor interacting protein 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
RRM2 ribonucleotide reductase M2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TLR4 toll-like receptor 4
TYMS thymidylate synthetase
XBP1 X-box binding protein 1