BRD-K92571446_WZ-3105_MCF10A_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K92571446_WZ-3105_MCF10A_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADD3 adducin 3 (gamma)
AKAP7 A kinase (PRKA) anchor protein 7
ANOS1 anosmin 1
BEX1 brain expressed, X-linked 1
CRYAB crystallin, alpha B
CXCL13 chemokine (C-X-C motif) ligand 13
E2F2 E2F transcription factor 2
EGR1 early growth response 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP7 fatty acid binding protein 7, brain
GPI glucose-6-phosphate isomerase
GPX3 glutathione peroxidase 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
LAPTM4B lysosomal protein transmembrane 4 beta
MYLK myosin light chain kinase
NDRG2 NDRG family member 2
OLFML3 olfactomedin-like 3
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PRKCB protein kinase C, beta
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP1 retinol binding protein 1, cellular
SEPT6 septin 6
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SNAP25 synaptosomal-associated protein, 25kDa
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TSPAN13 tetraspanin 13
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CDC25B cell division cycle 25B
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
DEGS1 delta(4)-desaturase, sphingolipid 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
FBXO28 F-box protein 28
HSPA6 heat shock 70kDa protein 6 (HSP70B')
JADE2 jade family PHD finger 2
MMP12 matrix metallopeptidase 12
MYC v-myc avian myelocytomatosis viral oncogene homolog
PLAUR plasminogen activator, urokinase receptor
PSD3 pleckstrin and Sec7 domain containing 3
RGS2 regulator of G-protein signaling 2
RIN2 Ras and Rab interactor 2
SCAND1 SCAN domain containing 1
SPP1 secreted phosphoprotein 1
STC1 stanniocalcin 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TKT transketolase
TRIM2 tripartite motif containing 2