BRD-K92571446_WZ-3105_HT29_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

213 genes differentially expressed following the BRD-K92571446_WZ-3105_HT29_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
ADM adrenomedullin
ALB albumin
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALPL alkaline phosphatase, liver/bone/kidney
AOX1 aldehyde oxidase 1
AQP1 aquaporin 1 (Colton blood group)
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASPN asporin
ATF3 activating transcription factor 3
BCL2A1 BCL2-related protein A1
CA4 carbonic anhydrase IV
CALD1 caldesmon 1
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD163 CD163 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD52 CD52 molecule
CD83 CD83 molecule
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLC Charcot-Leyden crystal galectin
CLU clusterin
COL11A1 collagen, type XI, alpha 1
CPE carboxypeptidase E
CPM carboxypeptidase M
CSRP2 cysteine and glycine-rich protein 2
CST3 cystatin C
CSTA cystatin A (stefin A)
CTSL cathepsin L
CTTN cortactin
CXCL8 chemokine (C-X-C motif) ligand 8
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYR61 cysteine-rich, angiogenic inducer, 61
DEFA4 defensin, alpha 4, corticostatin
DLX5 distal-less homeobox 5
DUSP2 dual specificity phosphatase 2
ECHDC3 enoyl CoA hydratase domain containing 3
EGR1 early growth response 1
ENO2 enolase 2 (gamma, neuronal)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
F13A1 coagulation factor XIII, A1 polypeptide
F8 coagulation factor VIII, procoagulant component
FOLR1 folate receptor 1 (adult)
FOS FBJ murine osteosarcoma viral oncogene homolog
FSCN1 fascin actin-bundling protein 1
G0S2 G0/G1 switch 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GLUL glutamate-ammonia ligase
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
GPX3 glutathione peroxidase 3
GUSBP3 glucuronidase, beta pseudogene 3
HDAC9 histone deacetylase 9
HIST1H1C histone cluster 1, H1c
HIST1H2BC histone cluster 1, H2bc
HIST1H2BG histone cluster 1, H2bg
HP haptoglobin
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDS iduronate 2-sulfatase
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
JAG1 jagged 1
KLF10 Kruppel-like factor 10
KRT14 keratin 14, type I
KRT6A keratin 6A, type II
LAMP3 lysosomal-associated membrane protein 3
LOX lysyl oxidase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MFAP2 microfibrillar-associated protein 2
MFAP5 microfibrillar associated protein 5
MIR22HG MIR22 host gene
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MT1M metallothionein 1M
MT1X metallothionein 1X
MTSS1 metastasis suppressor 1
MXRA7 matrix-remodelling associated 7
NPIPB3 nuclear pore complex interacting protein family, member B3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PAM peptidylglycine alpha-amidating monooxygenase
PCDH7 protocadherin 7
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRR7 proline rich 7 (synaptic)
PRSS21 protease, serine, 21 (testisin)
RAB31 RAB31, member RAS oncogene family
REEP5 receptor accessory protein 5
RIOK3 RIO kinase 3
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A1 secretoglobin, family 2A, member 1
SCP2 sterol carrier protein 2
SCPEP1 serine carboxypeptidase 1
SDC2 syndecan 2
SEPP1 selenoprotein P, plasma, 1
SEPT6 septin 6
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFN stratifin
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SNAI2 snail family zinc finger 2
SNX2 sorting nexin 2
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
STK26 serine/threonine protein kinase 26
TACC1 transforming, acidic coiled-coil containing protein 1
TEK TEK tyrosine kinase, endothelial
TFPI2 tissue factor pathway inhibitor 2
TMEM45A transmembrane protein 45A
TMSB15A thymosin beta 15a
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSC22D3 TSC22 domain family, member 3
TSPAN7 tetraspanin 7
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUSC3 tumor suppressor candidate 3
TWIST1 twist family bHLH transcription factor 1
VAV3 vav 3 guanine nucleotide exchange factor
WIF1 WNT inhibitory factor 1
YPEL5 yippee-like 5 (Drosophila)
ZNF264 zinc finger protein 264
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ACTG2 actin, gamma 2, smooth muscle, enteric
AGR2 anterior gradient 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ASCC3 activating signal cointegrator 1 complex subunit 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAZ1A bromodomain adjacent to zinc finger domain, 1A
CAPN6 calpain 6
CCNA2 cyclin A2
CDKN2A cyclin-dependent kinase inhibitor 2A
CLTC clathrin, heavy chain (Hc)
COA3 cytochrome c oxidase assembly factor 3
CSE1L CSE1 chromosome segregation 1-like (yeast)
DHRS2 dehydrogenase/reductase (SDR family) member 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
EMG1 EMG1 N1-specific pseudouridine methyltransferase
FABP7 fatty acid binding protein 7, brain
FBL fibrillarin
FCGBP Fc fragment of IgG binding protein
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GPX2 glutathione peroxidase 2
GRWD1 glutamate-rich WD repeat containing 1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
ITGA6 integrin, alpha 6
JCHAIN joining chain of multimeric IgA and IgM
KAZN kazrin, periplakin interacting protein
KEAP1 kelch-like ECH-associated protein 1
KRT18 keratin 18, type I
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTF lactotransferrin
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MCM3 minichromosome maintenance complex component 3
MELK maternal embryonic leucine zipper kinase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLPH melanophilin
MRPL12 mitochondrial ribosomal protein L12
MRPL17 mitochondrial ribosomal protein L17
MRPS2 mitochondrial ribosomal protein S2
MRPS35 mitochondrial ribosomal protein S35
MYLK myosin light chain kinase
MYO10 myosin X
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUP85 nucleoporin 85kDa
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRSS2 protease, serine, 2 (trypsin 2)
RAD23B RAD23 homolog B (S. cerevisiae)
RBM47 RNA binding motif protein 47
REXO2 RNA exonuclease 2
S100P S100 calcium binding protein P
SF3B3 splicing factor 3b, subunit 3, 130kDa
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
STK10 serine/threonine kinase 10
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM97 transmembrane protein 97
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TSPAN8 tetraspanin 8
UBE3C ubiquitin protein ligase E3C
UMPS uridine monophosphate synthetase
USP1 ubiquitin specific peptidase 1
XBP1 X-box binding protein 1