BRD-K92571446_WZ-3105_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K92571446_WZ-3105_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
AHSG alpha-2-HS-glycoprotein
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
C3 complement component 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCND2 cyclin D2
CD48 CD48 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC2B C-type lectin domain family 2, member B
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CST3 cystatin C
CXCL10 chemokine (C-X-C motif) ligand 10
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DSP desmoplakin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERO1L ERO1-like (S. cerevisiae)
FAM107A family with sequence similarity 107, member A
FAM171A1 family with sequence similarity 171, member A1
FASTKD5 FAST kinase domains 5
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
FOS FBJ murine osteosarcoma viral oncogene homolog
GMPR guanosine monophosphate reductase
GPX3 glutathione peroxidase 3
GSN gelsolin
HES1 hes family bHLH transcription factor 1
HIST1H1C histone cluster 1, H1c
HLF hepatic leukemia factor
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL17RB interleukin 17 receptor B
ITM2A integral membrane protein 2A
JAG1 jagged 1
KAZN kazrin, periplakin interacting protein
KIAA0125 KIAA0125
KIF14 kinesin family member 14
KRT19 keratin 19, type I
MAPK13 mitogen-activated protein kinase 13
MECOM MDS1 and EVI1 complex locus
MFAP5 microfibrillar associated protein 5
MLF1 myeloid leukemia factor 1
MMP9 matrix metallopeptidase 9
NQO1 NAD(P)H dehydrogenase, quinone 1
PAX8 paired box 8
PEG3 paternally expressed 3
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PON3 paraoxonase 3
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBP1 retinol binding protein 1, cellular
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SCGB2A1 secretoglobin, family 2A, member 1
SKAP2 src kinase associated phosphoprotein 2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SPARCL1 SPARC-like 1 (hevin)
SPON1 spondin 1, extracellular matrix protein
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSC22D1 TSC22 domain family, member 1
TUSC3 tumor suppressor candidate 3
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4C ADP-ribosylation factor-like 4C
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCNE2 cyclin E2
CCNF cyclin F
CDK12 cyclin-dependent kinase 12
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHIC2 cysteine-rich hydrophobic domain 2
CHN1 chimerin 1
CSTA cystatin A (stefin A)
CTSE cathepsin E
CXCL13 chemokine (C-X-C motif) ligand 13
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPYD dihydropyrimidine dehydrogenase
FOSL1 FOS-like antigen 1
FXYD5 FXYD domain containing ion transport regulator 5
FZD2 frizzled class receptor 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GATA3 GATA binding protein 3
GPATCH8 G patch domain containing 8
GPM6B glycoprotein M6B
GPRC5A G protein-coupled receptor, class C, group 5, member A
IGL immunoglobulin lambda locus
JADE2 jade family PHD finger 2
JMJD6 jumonji domain containing 6
KIAA1033 KIAA1033
LAMA3 laminin, alpha 3
LDLR low density lipoprotein receptor
MYBPC1 myosin binding protein C, slow type
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NNMT nicotinamide N-methyltransferase
PBX3 pre-B-cell leukemia homeobox 3
PDE4B phosphodiesterase 4B, cAMP-specific
PTGES prostaglandin E synthase
RHOB ras homolog family member B
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
UPP1 uridine phosphorylase 1
ZEB2 zinc finger E-box binding homeobox 2