BRD-K92571446_WZ-3105_HA1E_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the BRD-K92571446_WZ-3105_HA1E_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACKR3 atypical chemokine receptor 3
ADA adenosine deaminase
ADGRE5 adhesion G protein-coupled receptor E5
ADIRF adipogenesis regulatory factor
AHSP alpha hemoglobin stabilizing protein
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANGPTL2 angiopoietin-like 2
ANXA1 annexin A1
AQP1 aquaporin 1 (Colton blood group)
ARL4C ADP-ribosylation factor-like 4C
ASPN asporin
ATF3 activating transcription factor 3
BIK BCL2-interacting killer (apoptosis-inducing)
BSG basigin (Ok blood group)
C10ORF10 chromosome 10 open reading frame 10
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CD36 CD36 molecule (thrombospondin receptor)
CD52 CD52 molecule
CD9 CD9 molecule
CD99 CD99 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
CLEC3B C-type lectin domain family 3, member B
CLIC5 chloride intracellular channel 5
CLU clusterin
COL3A1 collagen, type III, alpha 1
COLEC12 collectin sub-family member 12
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CPT1A carnitine palmitoyltransferase 1A (liver)
CRABP2 cellular retinoic acid binding protein 2
CSTA cystatin A (stefin A)
CTSK cathepsin K
CXADR coxsackie virus and adenovirus receptor
DKK3 dickkopf WNT signaling pathway inhibitor 3
DUSP6 dual specificity phosphatase 6
EFNB2 ephrin-B2
EGR1 early growth response 1
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
EMP1 epithelial membrane protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
EPCAM epithelial cell adhesion molecule
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
F3 coagulation factor III (thromboplastin, tissue factor)
FBP1 fructose-1,6-bisphosphatase 1
FLT1 fms-related tyrosine kinase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45B growth arrest and DNA-damage-inducible, beta
GLUD1 glutamate dehydrogenase 1
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
HIST2H2BE histone cluster 2, H2be
HOXB2 homeobox B2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDS iduronate 2-sulfatase
IER3 immediate early response 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IL1R1 interleukin 1 receptor, type I
IRF6 interferon regulatory factor 6
JAG1 jagged 1
KLF10 Kruppel-like factor 10
KRT19 keratin 19, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
LAMP3 lysosomal-associated membrane protein 3
LAPTM5 lysosomal protein transmembrane 5
LDB2 LIM domain binding 2
LGALS3 lectin, galactoside-binding, soluble, 3
LRRC15 leucine rich repeat containing 15
LST1 leukocyte specific transcript 1
LTB lymphotoxin beta (TNF superfamily, member 3)
LYPD3 LY6/PLAUR domain containing 3
LYZ lysozyme
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A1 mannosidase, alpha, class 1A, member 1
MEF2C myocyte enhancer factor 2C
METRN meteorin, glial cell differentiation regulator
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1M metallothionein 1M
MT1X metallothionein 1X
NDRG1 N-myc downstream regulated 1
NPDC1 neural proliferation, differentiation and control, 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5E 5'-nucleotidase, ecto (CD73)
PCDH17 protocadherin 17
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PERP PERP, TP53 apoptosis effector
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTN pleiotrophin
PTPRC protein tyrosine phosphatase, receptor type, C
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A1 secretoglobin, family 2A, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDC4 syndecan 4
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFN stratifin
SFTPC surfactant protein C
SH3YL1 SH3 and SYLF domain containing 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPARCL1 SPARC-like 1 (hevin)
SPON1 spondin 1, extracellular matrix protein
SPRY4 sprouty homolog 4 (Drosophila)
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULF1 sulfatase 1
SYBU syntabulin (syntaxin-interacting)
TACC1 transforming, acidic coiled-coil containing protein 1
THY1 Thy-1 cell surface antigen
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM47 transmembrane protein 47
TPM4 tropomyosin 4
TRIB2 tribbles pseudokinase 2
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF264 zinc finger protein 264
ZNF331 zinc finger protein 331
ZNF544 zinc finger protein 544
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ASCC3 activating signal cointegrator 1 complex subunit 3
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
BASP1 brain abundant, membrane attached signal protein 1
CCNA2 cyclin A2
CENPA centromere protein A
CHEK2 checkpoint kinase 2
CLGN calmegin
CLTA clathrin, light chain A
COA3 cytochrome c oxidase assembly factor 3
CSE1L CSE1 chromosome segregation 1-like (yeast)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
GALE UDP-galactose-4-epimerase
GRB10 growth factor receptor-bound protein 10
GRWD1 glutamate-rich WD repeat containing 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXC6 homeobox C6
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
INSIG1 insulin induced gene 1
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KIF20A kinesin family member 20A
KPNB1 karyopherin (importin) beta 1
LAPTM4B lysosomal protein transmembrane 4 beta
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MARCKS myristoylated alanine-rich protein kinase C substrate
MATN2 matrilin 2
PFKP phosphofructokinase, platelet
PROM1 prominin 1
RBPMS RNA binding protein with multiple splicing
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RPA3 replication protein A3, 14kDa
SFRP1 secreted frizzled-related protein 1
SNX11 sorting nexin 11
SPDL1 spindle apparatus coiled-coil protein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI2 tissue factor pathway inhibitor 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TSPAN8 tetraspanin 8
WDR6 WD repeat domain 6
XBP1 X-box binding protein 1