BRD-K92571446_WZ-3105_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K92571446_WZ-3105_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ADK adenosine kinase
ANXA6 annexin A6
ARG2 arginase 2
CXADR coxsackie virus and adenovirus receptor
FERMT1 fermitin family member 1
FKBP3 FK506 binding protein 3, 25kDa
FOSB FBJ murine osteosarcoma viral oncogene homolog B
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
IER3 immediate early response 3
IGKC immunoglobulin kappa constant
INPP5F inositol polyphosphate-5-phosphatase F
LTA4H leukotriene A4 hydrolase
LXN latexin
MAOA monoamine oxidase A
MYO5C myosin VC
OAT ornithine aminotransferase
PBX3 pre-B-cell leukemia homeobox 3
PON3 paraoxonase 3
PRDX3 peroxiredoxin 3
RAB29 RAB29, member RAS oncogene family
RGS1 regulator of G-protein signaling 1
RGS10 regulator of G-protein signaling 10
SCG2 secretogranin II
SFN stratifin
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TUSC3 tumor suppressor candidate 3
UGDH UDP-glucose 6-dehydrogenase
ZDHHC6 zinc finger, DHHC-type containing 6

decreased expression

Symbol Name
ADM adrenomedullin
AGTR1 angiotensin II receptor, type 1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ARID4B AT rich interactive domain 4B (RBP1-like)
AURKA aurora kinase A
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BAMBI BMP and activin membrane-bound inhibitor
BHLHE40 basic helix-loop-helix family, member e40
C3 complement component 3
CBR3 carbonyl reductase 3
CCL5 chemokine (C-C motif) ligand 5
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEMIP cell migration inducing protein, hyaluronan binding
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL15A1 collagen, type XV, alpha 1
CST7 cystatin F (leukocystatin)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
FGFR2 fibroblast growth factor receptor 2
FZD7 frizzled class receptor 7
GATA3 GATA binding protein 3
GDF15 growth differentiation factor 15
GRIA2 glutamate receptor, ionotropic, AMPA 2
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
IGFBP5 insulin-like growth factor binding protein 5
LRIF1 ligand dependent nuclear receptor interacting factor 1
MAGEA12 melanoma antigen family A12
MED13 mediator complex subunit 13
MRPS30 mitochondrial ribosomal protein S30
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NNMT nicotinamide N-methyltransferase
NRIP1 nuclear receptor interacting protein 1
ORC1 origin recognition complex, subunit 1
PDGFA platelet-derived growth factor alpha polypeptide
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PROM1 prominin 1
RBM15 RNA binding motif protein 15
S100A8 S100 calcium binding protein A8
SCGB2A2 secretoglobin, family 2A, member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG8 SMG8 nonsense mediated mRNA decay factor
SPEN spen family transcriptional repressor
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFF1 trefoil factor 1
TGFBI transforming growth factor, beta-induced, 68kDa
TIMP1 TIMP metallopeptidase inhibitor 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLE4 transducin-like enhancer of split 4
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
WEE1 WEE1 G2 checkpoint kinase
WNT5A wingless-type MMTV integration site family, member 5A
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF217 zinc finger protein 217