BRD-K92571446_WZ-3105_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K92571446_WZ-3105_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP7 A kinase (PRKA) anchor protein 7
ANXA6 annexin A6
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
CD36 CD36 molecule (thrombospondin receptor)
CFD complement factor D (adipsin)
CHRDL1 chordin-like 1
COL9A3 collagen, type IX, alpha 3
CRLF1 cytokine receptor-like factor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FKBP11 FK506 binding protein 11, 19 kDa
FRZB frizzled-related protein
G0S2 G0/G1 switch 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
HSPB8 heat shock 22kDa protein 8
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
INPP5F inositol polyphosphate-5-phosphatase F
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KDM5D lysine (K)-specific demethylase 5D
LAPTM4B lysosomal protein transmembrane 4 beta
LY75 lymphocyte antigen 75
MCOLN1 mucolipin 1
METTL7A methyltransferase like 7A
PAM peptidylglycine alpha-amidating monooxygenase
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PLBD1 phospholipase B domain containing 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKCB protein kinase C, beta
RPS4Y1 ribosomal protein S4, Y-linked 1
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPON2 spondin 2, extracellular matrix protein
TRD T cell receptor delta locus
TSPAN8 tetraspanin 8
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARID4B AT rich interactive domain 4B (RBP1-like)
AURKA aurora kinase A
BIK BCL2-interacting killer (apoptosis-inducing)
CBR3 carbonyl reductase 3
CCNF cyclin F
CDC25A cell division cycle 25A
CEMIP cell migration inducing protein, hyaluronan binding
CHD7 chromodomain helicase DNA binding protein 7
CHIC2 cysteine-rich hydrophobic domain 2
DACH1 dachshund family transcription factor 1
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
EMP1 epithelial membrane protein 1
EPHB2 EPH receptor B2
FABP7 fatty acid binding protein 7, brain
FBXL12 F-box and leucine-rich repeat protein 12
FOSL2 FOS-like antigen 2
FZD7 frizzled class receptor 7
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
IER5 immediate early response 5
IRS2 insulin receptor substrate 2
KLK10 kallikrein-related peptidase 10
KLK6 kallikrein-related peptidase 6
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
NNMT nicotinamide N-methyltransferase
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRCAM neuronal cell adhesion molecule
PDZRN3 PDZ domain containing ring finger 3
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRO protein tyrosine phosphatase, receptor type, O
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100P S100 calcium binding protein P
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPEN spen family transcriptional repressor
SRGN serglycin
SULF1 sulfatase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THBS1 thrombospondin 1
TICAM1 toll-like receptor adaptor molecule 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNNT1 troponin T type 1 (skeletal, slow)
TRIB3 tribbles pseudokinase 3
XIST X inactive specific transcript (non-protein coding)