BRD-K92571446_WZ-3105_BT20_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K92571446_WZ-3105_BT20_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AQP1 aquaporin 1 (Colton blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCL2A1 BCL2-related protein A1
CLU clusterin
COCH cochlin
COL2A1 collagen, type II, alpha 1
CST3 cystatin C
DKK3 dickkopf WNT signaling pathway inhibitor 3
ENO1 enolase 1, (alpha)
EZR ezrin
FAM129A family with sequence similarity 129, member A
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FKBP1A FK506 binding protein 1A, 12kDa
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GEM GTP binding protein overexpressed in skeletal muscle
GSN gelsolin
HAMP hepcidin antimicrobial peptide
HSPB8 heat shock 22kDa protein 8
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
JUN jun proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
MOXD1 monooxygenase, DBH-like 1
MXRA7 matrix-remodelling associated 7
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAM peptidylglycine alpha-amidating monooxygenase
PCP4 Purkinje cell protein 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLTP phospholipid transfer protein
PRDX6 peroxiredoxin 6
SFTPA2 surfactant protein A2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STOM stomatin
TF transferrin
TNC tenascin C
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8
TUBA1A tubulin, alpha 1a
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
ARID4B AT rich interactive domain 4B (RBP1-like)
BIRC2 baculoviral IAP repeat containing 2
C1ORF116 chromosome 1 open reading frame 116
CBR3 carbonyl reductase 3
CCNE2 cyclin E2
CRABP2 cellular retinoic acid binding protein 2
CRISP3 cysteine-rich secretory protein 3
DEGS1 delta(4)-desaturase, sphingolipid 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
JADE2 jade family PHD finger 2
KLK10 kallikrein-related peptidase 10
KLK6 kallikrein-related peptidase 6
KYNU kynureninase
MARCKS myristoylated alanine-rich protein kinase C substrate
MIS12 MIS12 kinetochore complex component
NELL2 NEL-like 2 (chicken)
NVL nuclear VCP-like
PLA2G16 phospholipase A2, group XVI
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPP1 secreted phosphoprotein 1
SRGN serglycin
TACSTD2 tumor-associated calcium signal transducer 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLR4 toll-like receptor 4
XIST X inactive specific transcript (non-protein coding)