BRD-K92571446_WZ-3105_BT20_3_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K92571446_WZ-3105_BT20_3_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C10ORF10 chromosome 10 open reading frame 10
CD36 CD36 molecule (thrombospondin receptor)
COCH cochlin
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL2 chemokine (C-X-C motif) ligand 2
GSN gelsolin
HES1 hes family bHLH transcription factor 1
IER3 immediate early response 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL17RB interleukin 17 receptor B
JAG1 jagged 1
KRT19 keratin 19, type I
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LIPG lipase, endothelial
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX9 SRY (sex determining region Y)-box 9
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFF3 trefoil factor 3 (intestinal)
THBS4 thrombospondin 4
TM4SF1 transmembrane 4 L six family member 1
TSPAN8 tetraspanin 8
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ARID4B AT rich interactive domain 4B (RBP1-like)
C6ORF62 chromosome 6 open reading frame 62
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
EMX2 empty spiracles homeobox 2
EPS8L2 EPS8-like 2
FTH1 ferritin, heavy polypeptide 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
IFITM1 interferon induced transmembrane protein 1
IRS2 insulin receptor substrate 2
JADE2 jade family PHD finger 2
LDHB lactate dehydrogenase B
MAL mal, T-cell differentiation protein
MAP7 microtubule-associated protein 7
NR4A2 nuclear receptor subfamily 4, group A, member 2
SNAP25 synaptosomal-associated protein, 25kDa
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TRIM29 tripartite motif containing 29
TUBB6 tubulin, beta 6 class V
TYMS thymidylate synthetase
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)