BRD-K92571446_WZ-3105_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K92571446_WZ-3105_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA1 annexin A1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BCHE butyrylcholinesterase
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FKBP11 FK506 binding protein 11, 19 kDa
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HSPB8 heat shock 22kDa protein 8
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEFL neurofilament, light polypeptide
NR2F2 nuclear receptor subfamily 2, group F, member 2
OSBPL8 oxysterol binding protein-like 8
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PCDH9 protocadherin 9
PEG10 paternally expressed 10
PLK2 polo-like kinase 2
RGS2 regulator of G-protein signaling 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SIK1 salt-inducible kinase 1
SOX9 SRY (sex determining region Y)-box 9
TBL1X transducin (beta)-like 1X-linked
TFPI2 tissue factor pathway inhibitor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TSPAN8 tetraspanin 8
TUBB2B tubulin, beta 2B class IIb
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
ANXA3 annexin A3
CA2 carbonic anhydrase II
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CHN1 chimerin 1
CIAPIN1 cytokine induced apoptosis inhibitor 1
CRABP2 cellular retinoic acid binding protein 2
CTSH cathepsin H
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EMX2 empty spiracles homeobox 2
ESRP1 epithelial splicing regulatory protein 1
FGFR2 fibroblast growth factor receptor 2
LIMCH1 LIM and calponin homology domains 1
LOXL2 lysyl oxidase-like 2
MAP7 microtubule-associated protein 7
MFAP5 microfibrillar associated protein 5
PUF60 poly-U binding splicing factor 60KDa
RPA3 replication protein A3, 14kDa
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFTPB surfactant protein B
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
TMSB15A thymosin beta 15a
TNS3 tensin 3
TSPAN3 tetraspanin 3