BRD-K92571446_WZ-3105_BT20_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K92571446_WZ-3105_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAG3 BCL2-associated athanogene 3
BANK1 B-cell scaffold protein with ankyrin repeats 1
C1ORF115 chromosome 1 open reading frame 115
CD52 CD52 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRISP3 cysteine-rich secretory protein 3
EMP1 epithelial membrane protein 1
EMP3 epithelial membrane protein 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPS8 epidermal growth factor receptor pathway substrate 8
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAS Fas cell surface death receptor
FBP1 fructose-1,6-bisphosphatase 1
GLUL glutamate-ammonia ligase
GRB14 growth factor receptor-bound protein 14
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIST2H2BE histone cluster 2, H2be
IL7R interleukin 7 receptor
JMJD6 jumonji domain containing 6
KLF4 Kruppel-like factor 4 (gut)
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MLPH melanophilin
NELL2 NEL-like 2 (chicken)
NRGN neurogranin (protein kinase C substrate, RC3)
PLK1 polo-like kinase 1
PTN pleiotrophin
REEP5 receptor accessory protein 5
S100A12 S100 calcium binding protein A12
S100A7 S100 calcium binding protein A7
SFN stratifin
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
STC2 stanniocalcin 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFF1 trefoil factor 1
THUMPD1 THUMP domain containing 1
TMSB15A thymosin beta 15a

decreased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ARFIP2 ADP-ribosylation factor interacting protein 2
ARID4B AT rich interactive domain 4B (RBP1-like)
AURKB aurora kinase B
C8ORF4 chromosome 8 open reading frame 4
CPNE3 copine III
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EIF5 eukaryotic translation initiation factor 5
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
KRT18 keratin 18, type I
MAB21L2 mab-21-like 2 (C. elegans)
MAN1A1 mannosidase, alpha, class 1A, member 1
MAPK13 mitogen-activated protein kinase 13
MCM3 minichromosome maintenance complex component 3
MRPL12 mitochondrial ribosomal protein L12
MRPL57 mitochondrial ribosomal protein L57
NFIB nuclear factor I/B
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NIPSNAP1 nipsnap homolog 1 (C. elegans)
PLAC8 placenta-specific 8
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PYCARD PYD and CARD domain containing
SIK1 salt-inducible kinase 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNS3 tensin 3
TRIP6 thyroid hormone receptor interactor 6