BRD-K92428232_HY-50877_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K92428232_HY-50877_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ANKRD10 ankyrin repeat domain 10
ANPEP alanyl (membrane) aminopeptidase
ANXA5 annexin A5
ARID4B AT rich interactive domain 4B (RBP1-like)
BASP1 brain abundant, membrane attached signal protein 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DHCR24 24-dehydrocholesterol reductase
DMXL2 Dmx-like 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LUC7L3 LUC7-like 3 (S. cerevisiae)
MSMO1 methylsterol monooxygenase 1
NT5E 5'-nucleotidase, ecto (CD73)
RBM47 RNA binding motif protein 47
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)

decreased expression

Symbol Name
BAX BCL2-associated X protein
DLK1 delta-like 1 homolog (Drosophila)
EDNRA endothelin receptor type A
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GPM6B glycoprotein M6B
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
LYZ lysozyme
NID1 nidogen 1
PAX6 paired box 6
PCDH17 protocadherin 17
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RGS1 regulator of G-protein signaling 1
SPARCL1 SPARC-like 1 (hevin)
ZIC1 Zic family member 1