BRD-K92428232_HY-50877_NPC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K92428232_HY-50877_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
AIM1 absent in melanoma 1
BID BH3 interacting domain death agonist
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COLEC12 collectin sub-family member 12
CSTA cystatin A (stefin A)
DENND1B DENN/MADD domain containing 1B
EGFL6 EGF-like-domain, multiple 6
EPAS1 endothelial PAS domain protein 1
EXT1 exostosin glycosyltransferase 1
FAM129A family with sequence similarity 129, member A
FRY furry homolog (Drosophila)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GATA3 GATA binding protein 3
GPNMB glycoprotein (transmembrane) nmb
GUSBP11 glucuronidase, beta pseudogene 11
HOMER3 homer scaffolding protein 3
HSPA2 heat shock 70kDa protein 2
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL1RN interleukin 1 receptor antagonist
KRT18 keratin 18, type I
LAMP2 lysosomal-associated membrane protein 2
MAOA monoamine oxidase A
MME membrane metallo-endopeptidase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PMM2 phosphomannomutase 2
PRNP prion protein
PRUNE2 prune homolog 2 (Drosophila)
RPS4Y1 ribosomal protein S4, Y-linked 1
SDC1 syndecan 1
SHB Src homology 2 domain containing adaptor protein B
SPON2 spondin 2, extracellular matrix protein
TACSTD2 tumor-associated calcium signal transducer 2
TARP TCR gamma alternate reading frame protein
TCEA2 transcription elongation factor A (SII), 2
TRD T cell receptor delta locus
TRIB3 tribbles pseudokinase 3
WNT5A wingless-type MMTV integration site family, member 5A
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ANKRD10 ankyrin repeat domain 10
BIN1 bridging integrator 1
BST2 bone marrow stromal cell antigen 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CISD1 CDGSH iron sulfur domain 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLD dihydrolipoamide dehydrogenase
EGR1 early growth response 1
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
GCH1 GTP cyclohydrolase 1
HAT1 histone acetyltransferase 1
HLA-DMA major histocompatibility complex, class II, DM alpha
HLTF helicase-like transcription factor
IL6ST interleukin 6 signal transducer
KLF2 Kruppel-like factor 2
LAPTM4B lysosomal protein transmembrane 4 beta
LEF1 lymphoid enhancer-binding factor 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MARCKSL1 MARCKS-like 1
MMD monocyte to macrophage differentiation-associated
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NUP62 nucleoporin 62kDa
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PLAT plasminogen activator, tissue
PRDX2 peroxiredoxin 2
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTP4A1 protein tyrosine phosphatase type IVA, member 1
QDPR quinoid dihydropteridine reductase
QPCT glutaminyl-peptide cyclotransferase
RBPMS RNA binding protein with multiple splicing
RCAN1 regulator of calcineurin 1
RPIA ribose 5-phosphate isomerase A
SLC26A2 solute carrier family 26 (anion exchanger), member 2
STOM stomatin
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNC tenascin C
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TSPAN13 tetraspanin 13
TSPAN6 tetraspanin 6
YME1L1 YME1-like 1 ATPase