BRD-K92428232_GSK-461364_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K92428232_GSK-461364_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP3 aquaporin 3 (Gill blood group)
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
AURKA aurora kinase A
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCDC86 coiled-coil domain containing 86
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CLSTN1 calsyntenin 1
COL9A3 collagen, type IX, alpha 3
COTL1 coactosin-like F-actin binding protein 1
CXADR coxsackie virus and adenovirus receptor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL5 chemokine (C-X-C motif) ligand 5
CYR61 cysteine-rich, angiogenic inducer, 61
FXR1 fragile X mental retardation, autosomal homolog 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
IGL immunoglobulin lambda locus
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT14 keratin 14, type I
KRT81 keratin 81, type II
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
PALLD palladin, cytoskeletal associated protein
PEG10 paternally expressed 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP prolactin-induced protein
PLK1 polo-like kinase 1
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POSTN periostin, osteoblast specific factor
STOM stomatin
TATDN2 TatD DNase domain containing 2
TFRC transferrin receptor
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
C1ORF54 chromosome 1 open reading frame 54
CA2 carbonic anhydrase II
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD58 CD58 molecule
CDK1 cyclin-dependent kinase 1
CDK14 cyclin-dependent kinase 14
COPS7A COP9 signalosome subunit 7A
CSTA cystatin A (stefin A)
CXCL10 chemokine (C-X-C motif) ligand 10
EFS embryonal Fyn-associated substrate
ENO2 enolase 2 (gamma, neuronal)
EPS8 epidermal growth factor receptor pathway substrate 8
ETV1 ets variant 1
FXYD3 FXYD domain containing ion transport regulator 3
G0S2 G0/G1 switch 2
GLI2 GLI family zinc finger 2
GOLPH3L golgi phosphoprotein 3-like
GUSBP3 glucuronidase, beta pseudogene 3
HBB hemoglobin, beta
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT19 keratin 19, type I
LMO2 LIM domain only 2 (rhombotin-like 1)
LY96 lymphocyte antigen 96
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MLPH melanophilin
MRPS2 mitochondrial ribosomal protein S2
MUC4 mucin 4, cell surface associated
NREP neuronal regeneration related protein
PLBD1 phospholipase B domain containing 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTCH1 patched 1
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SRSF7 serine/arginine-rich splicing factor 7
TMEM45A transmembrane protein 45A
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP2A topoisomerase (DNA) II alpha 170kDa
TRIB2 tribbles pseudokinase 2
TSPAN13 tetraspanin 13
TSPAN31 tetraspanin 31
TST thiosulfate sulfurtransferase (rhodanese)
TXNDC9 thioredoxin domain containing 9
WNT5A wingless-type MMTV integration site family, member 5A