BRD-K92428232_GSK-461364_HT29_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-K92428232_GSK-461364_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADORA2B adenosine A2b receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDOA aldolase A, fructose-bisphosphate
BAG2 BCL2-associated athanogene 2
CBR3 carbonyl reductase 3
CDC20 cell division cycle 20
CHERP calcium homeostasis endoplasmic reticulum protein
CHI3L2 chitinase 3-like 2
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLDN10 claudin 10
CP ceruloplasmin (ferroxidase)
CX3CR1 chemokine (C-X3-C motif) receptor 1
DLC1 DLC1 Rho GTPase activating protein
DLK1 delta-like 1 homolog (Drosophila)
EGR1 early growth response 1
FCMR Fc fragment of IgM receptor
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
HBEGF heparin-binding EGF-like growth factor
HP haptoglobin
IGHM immunoglobulin heavy constant mu
INHBB inhibin, beta B
KRT17 keratin 17, type I
LDLR low density lipoprotein receptor
LTF lactotransferrin
MAP1B microtubule-associated protein 1B
MIR22HG MIR22 host gene
MTA1 metastasis associated 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OBSL1 obscurin-like 1
PEG3 paternally expressed 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRDX2 peroxiredoxin 2
PROM1 prominin 1
S100P S100 calcium binding protein P
SCGB2A1 secretoglobin, family 2A, member 1
SCRG1 stimulator of chondrogenesis 1
SDC2 syndecan 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLPI secretory leukocyte peptidase inhibitor
TIMP1 TIMP metallopeptidase inhibitor 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A

decreased expression

Symbol Name
ACOT7 acyl-CoA thioesterase 7
AGR2 anterior gradient 2
AKAP12 A kinase (PRKA) anchor protein 12
AMACR alpha-methylacyl-CoA racemase
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATAD2 ATPase family, AAA domain containing 2
CAST calpastatin
CCNE2 cyclin E2
CCNF cyclin F
CDC42 cell division cycle 42
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CPM carboxypeptidase M
DCN decorin
DNTT DNA nucleotidylexotransferase
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EPM2AIP1 EPM2A (laforin) interacting protein 1
FAM111A family with sequence similarity 111, member A
FAM134B family with sequence similarity 134, member B
FBP1 fructose-1,6-bisphosphatase 1
FHL1 four and a half LIM domains 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
HIST1H2BG histone cluster 1, H2bg
HMGB2 high mobility group box 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
IGF1R insulin-like growth factor 1 receptor
IL17RB interleukin 17 receptor B
KIAA0101 KIAA0101
KIF11 kinesin family member 11
LGALS3 lectin, galactoside-binding, soluble, 3
LUM lumican
MAOA monoamine oxidase A
MID1 midline 1
MSH6 mutS homolog 6
MXI1 MAX interactor 1, dimerization protein
NFIB nuclear factor I/B
NUSAP1 nucleolar and spindle associated protein 1
PTN pleiotrophin
PTTG1 pituitary tumor-transforming 1
RUFY3 RUN and FYVE domain containing 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPAG4 sperm associated antigen 4
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STC1 stanniocalcin 1
TFPI2 tissue factor pathway inhibitor 2
TMSB15A thymosin beta 15a
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
ZFPM2 zinc finger protein, FOG family member 2