BRD-K92428232_GSK-461364_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K92428232_GSK-461364_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
AREG amphiregulin
AURKA aurora kinase A
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
COCH cochlin
LEF1 lymphoid enhancer-binding factor 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MYO5A myosin VA (heavy chain 12, myoxin)
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
ZMYM2 zinc finger, MYM-type 2

decreased expression

Symbol Name
ARHGAP29 Rho GTPase activating protein 29
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CALD1 caldesmon 1
CCNF cyclin F
CDCA4 cell division cycle associated 4
CDK1 cyclin-dependent kinase 1
CFLAR CASP8 and FADD-like apoptosis regulator
CPD carboxypeptidase D
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL10 chemokine (C-X-C motif) ligand 10
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
MGP matrix Gla protein
NFIB nuclear factor I/B
NREP neuronal regeneration related protein
RNASE4 ribonuclease, RNase A family, 4
RRM2 ribonucleotide reductase M2
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UBE2C ubiquitin-conjugating enzyme E2C
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WWTR1 WW domain containing transcription regulator 1