BRD-K92301463_-666_SW620_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K92301463_-666_SW620_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ARG2 arginase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF4 activating transcription factor 4
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
BAG3 BCL2-associated athanogene 3
C6ORF62 chromosome 6 open reading frame 62
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CTH cystathionine gamma-lyase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DSP desmoplakin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
FCMR Fc fragment of IgM receptor
FXR1 fragile X mental retardation, autosomal homolog 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGHM immunoglobulin heavy constant mu
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT6A keratin 6A, type II
MME membrane metallo-endopeptidase
MNAT1 MNAT CDK-activating kinase assembly factor 1
NDRG1 N-myc downstream regulated 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NQO1 NAD(P)H dehydrogenase, quinone 1
NT5E 5'-nucleotidase, ecto (CD73)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
POPDC3 popeye domain containing 3
QPCT glutaminyl-peptide cyclotransferase
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3YL1 SH3 and SYLF domain containing 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
STC2 stanniocalcin 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULF1 sulfatase 1
TBX3 T-box 3
TMEM30B transmembrane protein 30B
TPD52 tumor protein D52
TPD52L1 tumor protein D52-like 1
TXNRD1 thioredoxin reductase 1
UPP1 uridine phosphorylase 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
C3 complement component 3
CCL5 chemokine (C-C motif) ligand 5
CCNA2 cyclin A2
CD36 CD36 molecule (thrombospondin receptor)
CES1 carboxylesterase 1
COG2 component of oligomeric golgi complex 2
COPS7A COP9 signalosome subunit 7A
CXCL14 chemokine (C-X-C motif) ligand 14
DAPK1 death-associated protein kinase 1
GPM6A glycoprotein M6A
HOPX HOP homeobox
MGP matrix Gla protein
NCAM1 neural cell adhesion molecule 1
PDGFA platelet-derived growth factor alpha polypeptide
RGS5 regulator of G-protein signaling 5
SPARCL1 SPARC-like 1 (hevin)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
WFS1 Wolfram syndrome 1 (wolframin)