BRD-K92301463_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K92301463_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BHLHE40 basic helix-loop-helix family, member e40
C5AR1 complement component 5a receptor 1
CA1 carbonic anhydrase I
CD52 CD52 molecule
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHA2 EPH receptor A2
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GAL galanin/GMAP prepropeptide
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IER2 immediate early response 2
IER3 immediate early response 3
IER5 immediate early response 5
IL1R2 interleukin 1 receptor, type II
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NR4A1 nuclear receptor subfamily 4, group A, member 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIP prolactin-induced protein
PLAUR plasminogen activator, urokinase receptor
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUBB2A tubulin, beta 2A class IIa
TXNRD1 thioredoxin reductase 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
AEBP1 AE binding protein 1
CENPA centromere protein A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
HOXC6 homeobox C6
IGFBP5 insulin-like growth factor binding protein 5
SKAP2 src kinase associated phosphoprotein 2