BRD-K92301463_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K92301463_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAG3 BCL2-associated athanogene 3
CA12 carbonic anhydrase XII
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHIC2 cysteine-rich hydrophobic domain 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
FRY furry homolog (Drosophila)
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
IER5 immediate early response 5
KYNU kynureninase
LHFPL2 lipoma HMGIC fusion partner-like 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MUC5B mucin 5B, oligomeric mucus/gel-forming
NPC1 Niemann-Pick disease, type C1
NQO1 NAD(P)H dehydrogenase, quinone 1
PTN pleiotrophin
RGS2 regulator of G-protein signaling 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACTA2 actin, alpha 2, smooth muscle, aorta
ASPN asporin
CCDC85B coiled-coil domain containing 85B
CPE carboxypeptidase E
DPYSL3 dihydropyrimidinase-like 3
HOXA5 homeobox A5
ISG15 ISG15 ubiquitin-like modifier
LRRC41 leucine rich repeat containing 41
MGP matrix Gla protein
OLFM4 olfactomedin 4
PXDN peroxidasin
RGS5 regulator of G-protein signaling 5
THBS2 thrombospondin 2
ZMIZ1 zinc finger, MIZ-type containing 1